RA Flare Pathway Staff | March 2, 2021 Review our article: "Study Elucidates Potential Flare Pathways in Rheumatoid Arthritis," The Rheumatologist, December 2020. Research in The New England Journal of Medicine has opened new avenues for exploring the pathophysiology of disease flares in rheumatoid arthritis. Dana E. Orange, MD, assistant professor of clinical investigation at the Rockefeller University and assistant attending rheumatologist at the Hospital for Special Surgery, New York, explains, “We started this study because we noticed a gap in understanding how rheumatoid arthritis develops—a gap between the known risk factors for developing a diagnosis of rheumatoid arthritis and the actual patient experience of flares.” Which of the following describes a PRIME cell? A. A new type of antigen-presenting cells described in patients with RA B. A pre-inflammatory mesenchymal cell, with characteristics similar to synovial fibroblasts C. A myeloid precursor cell identified in the spleen of RA patients D. A subtype of hepatocyte involved in metabolism of methotrexate None Time's up