Gout: Infusion Reactions Staff | May 25, 2022 The 2020 ACR Guideline for the Management of Gout, which serves as the starting point for the clinical management of gout patients, is discussed in our article, "Clinical Insights into Gout Management: Q&A with Dr. Tuhina Neogi." And a guide to the drugs available to treat the disease is provided. Small studies have been conducted that demonstrate lower risks for pegloticase infusion reactions due to antibodies when concomitantly using which of the following: Methotrexate Mycophenalate mofetil Sulfasalazine with hydroxychloroquine A or B All of the above None Time's up