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An official publication of the ACR and the ARP serving rheumatologists and rheumatology professionals

Systemic Lupus Erythematosus FocusRheum

Systemic lupus erythematosus (SLE or lupus) is a chronic disease that causes systemic inflammation and affects multiple organs. How do we identify anti-nuclear antibody (ANA) positive patients who may develop full-blown SLE? What therapies are the most effective for which patients? Do biomarkers exist for lupus nephritis (LN)? These are some of the questions lupus expert Graciela S. Alarcón, MD, MPH, MACR, explored in the research abstracts presented at ACR Convergence 2024. Read her commentary, and explore our collection of research reviews, case reports and clinical articles on advances in the diagnosis and management of SLE. Features are added often, so check back frequently.

FEATURED ARTICLE: Helping Patients with SLE Thrive

 

ACR Convergence 2024

Lupus Arthritis: Experts Describe Strides Made in Understudied Condition

ACR Convergence 2024—Arthritis symptoms related to lupus are a bit of a trouble spot for clinicians, with limited data to guide treatment and overlap with other conditions, experts said in a session at ACR Convergence. Lupus arthritis (LA), present in 95% of patients with lupus, is the main cause of work-related disability and is a…

Bringing Lupus into the Light

With more than 350 research abstracts on systemic lupus erythematosus, lupus nephritis and related conditions accepted for presentation at ACR Convergence 2024, we’re happy to announce that Graciela S. Alarcón, MD, MPH, has accepted the monumental task of reviewing the abstracts and identifying those most likely to make a difference to clinical practice or lead…

How to Manage Lupus Nephritis: A New Guideline Introduced

A new guideline, the 2024 Updated ACR Guideline for the Diagnosis and Treatment of Lupus Nephritis, is being introduced at ACR Convergence 2024 on Monday, Nov. 18. In the session, Lisa Sammaritano, MD, professor of clinical medicine at Weill Cornell Medicine and Hospital for Special Surgery, New York, will discuss the guideline development process and…

Building a More Equitable Future in Lupus Care

The Dubois Memorial Lecture at ACR Convergence 2024 on Nov. 16 will be delivered by Candace Feldman, MD, MPH, ScD. Dr. Feldman is a rheumatologist and social epidemiology researcher at Brigham and Women’s Hospital/Harvard Medical School, Boston. Her lecture, Building a More Equitable Future in Lupus Care and Outcomes, will discuss the persistent and profound…

Personalize Your Pediatric Lupus Care

On Nov. 16, the ACR Convergence 2024 session Toward Personalized Medicine in Pediatric Lupus will present important recent findings in the pathophysiology of pediatric lupus. Virginia Pascual, MD, is program director of an NIAID-funded Autoimmunity Center of Excellence and a NIAMS-funded Center for Lupus Research at Weill Cornell Medical College, New York. Her laboratory is…

Research, Case Reports & More

10 Things to Know about Lupus

SLE treatment is rapidly evolving as new therapies are developed & approved. Here are 10 key insights for clinicians.

Lupus & Nightmares

Dr. David D’Cruz’s research attempts to help patients make sense of chronic nightmares, an understudied symptom of lupus.

Editor's Pick

B Cell-Depleting Therapy in SLE

“SLE has long been a disease with many clinical manifestations but few treatment options,” says Physician Editor Bharat Kumar, explaining why he thinks this article is a must-read. “That’s rapidly changing with advances in our knowledge of lupus, especially in the role of B-cells in triggering the onset and perpetuating disease activity of lupus.”