Finally, treatment with alendronate was not associated with increased risk of mild upper gastrointestinal tract symptoms or peptic ulcers. Researchers also saw no cases of incident drug-induced osteonecrosis and only one case of femoral shaft fracture in each group.
Lara C. Pullen, PhD, is a medical writer based in the Chicago area.
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Reference
- Axelsson KF, Nilsson AG, Wedel H, et al. Association between alendronate use and hip fracture risk in older patients using oral prednisolone. JAMA. 2017 Jul 11;318(2):146–155. doi: 10.1001/jama.2017.8040.