When the investigators examined the connection between CBFV variability and clinical variables, they found insomnia hypersomnia and fatigue were overall inversely associated with variability in the second VLF and low- and high-frequency components. The authors conclude that CBFV variability analysis may be a promising tool for characterizing fibromyalgia pathology, as well as for understanding facets of health-related quality of life.
Lara C. Pullen, PhD, is a medical writer based in the Chicago area.
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Reference
- Montoro CI, Duschek S, Schuepbach D, et al. Cerebral blood flow variability in fibromyalgia syndrome: Relationships with emotional, clinical and functional variables. PLoS One. 2018 Sep 20;13(9):e0204267.