Final Thoughts
SLE patients have heterogeneous manifestations of disease, and our SLE toolbox is beginning to match that diversity. When selecting a therapy, Dr. Aringer reminded us that not all SLE symptoms represent active autoimmunity, and therapies often need months to work. He concluded, “Take the individual SLE organ spectrum into account when choosing a drug. Be aware of the risks and uncertainties of off-label therapy, while bearing in mind that these patients need help, and there isn’t a lot that’s formally approved just yet.”
Samantha C. Shapiro, MD, is an academic rheumatologist and an affiliate faculty member of the Dell Medical School at the University of Texas at Austin. She is also a member of the ACR Insurance Subcommittee.
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