During her own fellowship training, Dr. Blazer benefited from mentorship by Jill P. Buyon, MD, director of the Division of Rheumatology and the Lupus Center at NYU Langone, New York. “She is the person who encouraged me to think about doing bench science. So with these [LRA] grants, we are going to be able to provide mentorship opportunities for other trainees of color, an important step in improving that exposure.”
Dr. Blazer’s award enables her to continue her current line of research focusing on genetic variants of the apolipoprotein L1 (APOL1) gene, which have been linked to both atherosclerosis and renal disease in populations of African ancestry. A significant number of African Americans carry these mutations, a baseline genetic risk that is heightened with the development of lupus.
Dr. Blazer will also use the LRA award to further her work with collaborators in Ghana and Nigeria. She received the Commitment to Fellow and Faculty Development Award in 2018 from the Nigerian Society for Rheumatology.
In the U.S., she will be laying the groundwork for other studies that examine the interplay between genetic predisposition and environmental factors, such as structural racism and economic deprivation.
Dr. Blazer spends a lot of time with her patients early during their treatment, empowering them with education about their condition. That foundation of trust then becomes the basis for well-considered decisions about research study participation. “I think well-informed patients who are in a trusting environment are more than happy to participate in research,” she says.
Recipients of Postdoctoral Award to Promote Diversity in Lupus Research
Ruth Fernandez Ruiz, MD, of the Hospital for Special Surgery, New York City, is evaluating the impact of genetic variants in lupus progression. “I am thrilled and honored to be one of the inaugural recipients of the Diversity in Lupus Research Awards,” she says. “This funding will be instrumental in continuing my contributions to SLE research and advancing my academic career. I believe that the Diversity in Lupus Research award program by the LRA is a great initiative to address the profound underrepresentation of minorities in biomedical research.”
Vanessa Sue Wacleche, PhD, a research fellow at Brigham and Women’s Hospital, Boston, is investigating peripheral T helper cells in lupus. “I feel blessed and humbled to receive this award,” she says. “I’m beyond excited to make a scientific contribution to understand better the immunopathology of lupus and propose therapeutic avenues.”