One participant in the triamcinolone-lidocaine group with a bioprosthetic aortic valve died from subacute bacterial endocarditis four months after the intervention, deemed possibly related to the trial treatment. The authors advise “caution… in patients with risk factors for, or signs of, infection.”
In community settings, they conclude, “an ultrasound guided intra-articular hip injection of corticosteroid and local anesthetic, administered with advice and education, is a clinically effective treatment for rapid and sustained symptom response compared with advice and education alone for people with hip osteoarthritis.”
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Reference
- Paskins Z, Bromley K, Lewis M, et al. Clinical effectiveness of one ultrasound guided intra-articular corticosteroid and local anaesthetic injection in addition to advice and education for hip osteoarthritis (HIT trial): Single blind, parallel group, three arm, randomised controlled trial. BMJ. 2022 Apr 6;377:e068446.