Molecular Differences Between Pediatric & Adult Psoriasis Plaques

“Despite the differences, we often treat adult and pediatric psoriasis using similar strategies,” he says.

“Over the past two to three decades, advances in the understanding of what causes psoriasis has led to the development of more sophisticated, targeted therapies—but these have, for the most part, been focused on adult disease,” he observes.

“This is an important study that addresses differences in adult and pediatric psoriasis at a molecular level,” he says. “This improved understanding of the cellular and molecular pathways that are active in pediatric psoriasis will help us to tailor our treatments specifically to this population, and lead to the development of newer, safer therapies.”

Reference

1. Cordoro KM, Hitraya-Low M, Taravati K, et al. Skin-infiltrating, interleukin-22-producing T cells differentiate pediatric psoriasis from adult psoriasis. J Am Acad Dermatol. 2017 Jun 14. pii: S0190-9622(17)31735-8. doi: 10.1016/j.jaad.2017.05.017. [Epub ahead of print]