Nintedanib Slows Lung Deterioration in General Fibrosing Interstitial Lung Disease

Side effects led to a permanent reduction in dose among 33.1% of nintedanib patients compared with 4.2% of those getting placebo.

“The use of nintedanib may slow the disease progression, but our challenge for the future is to design studies that identify earlier targets to prevent the establishment of this still highly morbid condition,” Dr. Goldberg says.

References

Flaherty KR, Wells AU, Cottin V, et al. Nintedanib in progressive fibrosing interstitial lung diseases. N Engl J Med. 2019 Sep 29. [Epub ahead of print]
Goldberg HJ. Understanding progressive fibrosing interstitial lung disease through therapeutic trials. N Engl J Med. 2019 Sep 29. [Epub ahead of print]

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