(Reuters)—The U.S. National Institutes of Health (NIH) is testing a booster shot of COVID-19 vaccines in people with autoimmune diseases who have not responded well to the primary vaccine course. The mid-stage study will be conducted among about 600 participants aged 18 and above who have been fully vaccinated with shots from either Pfizer Inc.,…

In Memoriam: Remembering William R. Palmer, MD, MACR
William “Bill” R. Palmer, MD, MACR, passed away on Aug. 5, 2021, from highly aggressive, metastatic thyroid carcinoma. He was surrounded by his loving family. Continuing a lifelong pattern, he was courageous, dignified and loving through his last moments. I first met Bill on July 1, 1974—my first day of my medical internship at Albany…

Kaitlyn Brittan, MD: ‘Advocacy Tells Me I Have a Voice’
Rheumatology advocacy added focus and purpose to Dr. Brittan’s medical training and now, in the rheumatology division at the University of Nebraska Medical Center, strengthens her relationships with colleagues and patients alike.

2-Year Extension Study Supports Voclosporin to Treat Patients with Lupus Nephritis
Research has shown voclosporin in combination with MMF and low-dose steroids benefits patients with lupus nephritis, significantly increasing the speed of remission. New data from an ongoing extension study demonstrate a positive risk/benefit profile.

COVID-19 Vaccine Efficacy & Safety Discussed at Town Hall
At a recent ACR town hall, panelists described immune responses and side effects of COVID-19 vaccination in patients with rheumatic disease, along with ways to leverage monoclonal antibody treatments, especially in light of virus variants.

The ACR Responds to CVS Caremark Prior Authorization Changes
The ACR sent a letter to CVS Caremark detailing how recent updates to its prior authorization forms for many biologic drugs are increasing the paperwork burden for rheumatology practices and hurting patients’ timely access to treatment.

RISE Registry Stakeholders Discuss Initiatives, Successes at Annual Strategy Summit
On Aug. 6, practice managers, clinicians and researchers gathered with ACR and RISE staff and volunteers to discuss the registry’s development and future.
Infections, Low IgG Seen in Kids Receiving Rituximab for Rheumatic Disease
NEW YORK (Reuters Health)—A significant proportion of children with rheumatic diseases develop new-onset hypogammaglobulinemia and infections following treatment with the monoclonal antibody rituximab, according to new U.S. research. “Increased risk appeared to be mediated, at least in part, by exposure to pulse dose corticosteroids,” write Marc Natter, MD, of Harvard Medical School and Boston Children’s…
EU Evaluates Tocilizumab as COVID-19 Treatment
(Reuters)—Europe’s drugs regulator said on Monday it was evaluating the use of Roche’s arthritis drug, tocilizumab, in hospitalized adults with severe COVID-19, its latest review of a potential coronavirus treatment. Tocilizumab, sold by Roche as Actemra and RoActemra, has shown promise in clinical trials in treating COVID-19, and was approved by U.S. health regulators in…

ACR Update on Tocilizumab Shortages
ATLANTA—The ACR is actively engaged with the U.S. Food & Drug Administration (FDA) Center for Drug Evaluation and Research (CDER) drug shortage team as they work with the manufacturer to resolve current shortages of tocilizumab (Actemra). Demand for tocilizumab has outpaced supply, with demand increasing after the FDA’s June 24 Emergency Use Authorization (EUA) for…
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