(Reuters Health)—Only 19 U.S. states mandate that pharmacists fill prescriptions for brand-name small molecule drugs with generics when available, with the 31 remaining states allowing but not requiring these substitutions, a new study finds. Researchers examined laws on the books as of September 2019 pertaining to generic substitution of small molecule drugs, as well as…
After COVID-19-Associated MIS-C, Immune Changes Resolve
NEW YORK (Reuters Health)—A new study of multisystem inflammatory syndrome in children (MIS-C) shows that the immune system is profoundly altered during acute illness, but gradually returns back to normal. MIS-C is distinct from both COVID-19 and Kawasaki disease, but is associated with previous SARS-CoV-2 infection, the immunological profiling study reveals. Dr. Manu Shankar-Hari, an…

For RA Patients, Functional Disability May Precede Diagnosis
In a study, researchers found rheumatoid arthritis patients experience a persistent burden of functional disability regardless of disease duration, age or gender.

Rituximab as Maintenance Therapy for Difficult-to-Treat SLE
For some patients with systemic lupus erythematosus, regular repeated treatment with rituximab may prevent disease flare, according to a study from Cassia et al.

Biologics May Prevent Cardiovascular Events in RA Patients
RA patients experience a higher rate of cardiovascular disease (CVD) events than controls. In a new study, Karpouzas et al. determined that current biologic disease-modifying anti-rheumatic drug use is associated with reduced long-term CVD risk, protective calcification of noncalcified lesions and a lower likelihood of new plaque formation in patients with early atherosclerosis.

Dendritic Cells as Therapeutics: The New Frontier
Cancer treatments, organ transplants and rheumatologic diseases—dendritic cells are being used throughout medicine to create innovative treatments, according to presenters of a virtual session during the European e-Congress of Rheumatology.

Artificial Intelligence in Medicine: The Future Is Now
Advancements in technology and artificial intelligence designed to aid rheumatologists in diagnosing patients and predicting mortality risk were discussed in depth during a session of the European e-Congress of Rheumatology.

Non-Radiographic Axial Spondyloarthritis Recognized with ICD-10 Code
The new diagnostic code should streamline billing for treatment of nr-axSpA, better define the spectrum of spondyloarthritic diseases and enable new research strategies into these conditions.
2020 State Legislative Roundup: The Year That Could Have Been & the Year That Was
The COVID-19 pandemic and response disrupted state legislative sessions and agendas in 2020, leaving many ACR priorities unfulfilled and highlighting the urgent need for vocal rheumatology leaders in Washington, D.C., and state capitols.

Advocacy 101 Teaches Legislative, Advocacy Basics
Bharat Kumar, MD, Advocacy 101 coordinator and Government Affairs Committee member, describes the virtual program designed to educate and empower rheumatology fellows in training, program directors and ARP members to advocate for issues that affect rheumatology practices and patients in advance of the Advocates for Arthritis that will take place virtually in September.
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