The FDA has approved abatacept to treat adults with active psoriatic arthritis. In clinical trials, the treatment has proved effective in both intravenous and subcutaneous forms…
Genetic Analysis Provides Insights into How Human Growth Is Linked to OA
Research has shed light on the genetic mutations that link GDF5 with arthritis and height. An ancient regulatory variant in GROW1 has been repeatedly selected in humans in northern environments, explaining the high frequency of a GDF5 haplotype that increases arthritis susceptibility…
Guidelines on Advice for Low Back Pain at Odds with Clinical Trial Results
NEW YORK (Reuters Health)—Advice is considered an effective treatment for acute low back pain (LBP), but neither clinical trials nor guidelines include adequate detail on what this advice should be, or how doctors should deliver it, according to a new review. And half of the advice topics included in guidelines were discordant with evidence from…
U.S. House Panel Spotlights Use of FDA Rules to Slow Generic Drugs
WASHINGTON (Reuters)—Republican and Democratic lawmakers on Thursday discussed ways to prevent drugmakers from using rules developed to safeguard patients to instead block the sale of cheaper medicines. The focus at a hearing, held by members of the House Judiciary Committee’s antitrust subcommittee, was on the use by some brand name drug companies of a U.S….
Republican Bid to Gut Obamacare Fails in Senate
WASHINGTON (Reuters)—A U.S. Senate led by Donald Trump’s fellow Republicans dealt the president a harsh blow on Friday, failing to move ahead with a major campaign promise to dismantle Obamacare as they fell one vote short of passing healthcare legislation. Three senators—John McCain (R-Az.), Susan Collins (R-ME) and Lisa Murkowski (R-Ala.)—joined Senate Democrats in the…
What Rheumatologists Are Paid
A 2017 survey showed that rheumatologists’ pay has plateaued. And according to Anne Bass, MD, many cognitive fields, such as pediatrics and endocrinology, remain underpaid due to the current reimbursement structure…
As Drug Prices Drop, Generics Makers Fight Back with Deals
NEW YORK (Reuters)—Generic drug makers are turning to mergers and acquisitions to shield themselves against a concerted effort by U.S. regulators to crack down on steep drug prices. Impax Laboratories Inc, Perrigo Company Plc and Alvogen Inc have been talking to advisers about strategic options for their generics businesses, ranging from acquisitions to increase scale…
U.S. Senate Mulls Bare-Bones Healthcare Bill; Marathon of Voting Expected
WASHINGTON (Reuters)—U.S. Senate Republicans embarked on Thursday on another push to unravel Obamacare, working on a stripped-down bill after failing to pass broader legislation and complete a seven-year campaign to gut a law that extended health coverage to millions. Republicans leaders hope a so-called skinny bill can draw enough votes to pass despite unified Democratic…
U.S. Senator Expands Opioid Probe to Distributors, Drugmakers
(Reuters)—U.S. Democratic Senator Claire McCaskill on Thursday expanded an investigation into the causes of the opioid crisis plaguing the country, seeking information from four more drugmakers and three drug distributors. The top-ranking Democrat on the Senate Homeland Security and Governmental Affairs Committee is focusing on the distribution of opioids and the efforts companies made to…
U.S. Senate Rejects Obamacare Repeal Again, Eyes a ‘Skinny’ Bill
WASHINGTON (Reuters)—Republicans in the U.S. Senate fell short again on Wednesday in their effort to end Obamacare, rejecting a measure to repeal large portions of President Barack Obama’s signature law that has provided health insurance to millions of Americans. But Republican Senate leaders, struggling to keep a seven-year-old promise to unravel the law, already were…
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