NEW YORK (Reuters Health)—More than 40% of patients with early inflammatory back pain suggestive of axial spondyloarthritis (SpA) show bone loss over the course of two years, according to French researchers. SpA is known to be associated with bone loss at the spine and the hip and an increased risk of vertebral fractures. To investigate…
Psoriasis Tied to Increased Risk of Major Depression
NEW YORK (Reuters Health)—People with psoriasis are twice as likely as others to have major depression, according to data from the National Health and Nutrition Examination Survey (NHANES). In earlier work, psoriasis has been linked to depression, anxiety and substance abuse. Studies have shown that both depression and psoriasis are associated with cardiovascular disease, which…
Immunotherapy May Be Effective for Some Patients with Autoimmune Cerebellar Ataxia
NEW YORK (Reuters Health)—Immunotherapy appears to yield neurological improvements in some patients with autoimmune cerebellar ataxia, especially those with nonparaneoplastic disorders, researchers report. “I was surprised that so many patients responded to immunotherapy (steroids, intravenous immunoglobulin (IVIg), and plasma exchange) and remained ambulatory,” Dr. Andrew McKeon from Mayo Clinic in Rochester, Minn., told Reuters Health…
Tabalumab Modestly Effective in Systemic Lupus Erythematosus
NEW YORK (Reuters Health)—Tabalumab, a monoclonal antibody to B-cell activating factor, was modestly better than placebo in relieving symptoms of systemic lupus erythematosus (SLE), according to results from the ILLUMINATE-2 trial. “Lupus is a complicated disease that does not behave the same way in all patients who share the clinical symptoms,” Dr. Joan T. Merrill…
Biotechs Extend Selloff as Pricing Concerns Intensify
NEW YORK (Reuters)—U.S. biotech shares extended their recent downward spiral on Tuesday as concerns about drug pricing continued to plague the sector while disappointing news from Illumina and other companies added to selling pressure. The Nasdaq Biotechnology index, down 4%, has now fallen about 17% since just before Hillary Clinton, front-runner to be the Democratic nominee…
Complex Patients More Likely to Switch from Medicare Advantage
NEW YORK (Reuters Health)—Medicare Advantage plans might not be meeting the needs of patients requiring the costliest and most complex levels of care, a new study suggests. Between 2010 and 2011, such patients were more likely to switch from Medicare Advantage plans to traditional Medicare, rather than vice versa, researchers found. The results suggest people…

Ustekinumab Can Be Used to Safely Treat Teens & More
A recent study showed ustekinumab can be used to treat teens with moderate to severe psoriasis. Also, Phase 2 trials for an analgesic combination drug show it holds promise for reducing post-operative pain…

How Hospitals Rank in Treating Childhood-Onset SLE
A recent study of how medical facilities in three countries meet minimum care standards for patients with childhood-onset systemic lupus erythematosus found a wide variation in quality of care…
Does Insomnia in Patients with Knee OA Affect Pain?
New research explores the correlation between insomnia and pain in patients with knee osteoarthritis (OA). After conducting a multimodal sleep study, researchers from Johns Hopkins University in Baltimore uncovered a combined effect between catastrophizing and disturbed sleep, resulting in increased pain sensitivity, specifically central sensitization, for knee OA…
Weight-Bearing Exercise Eases Knee Osteoarthritis, Temporarily
(Reuters Health)—A program of weight-bearing exercise reduces pain and improves joint function, at least for two to six months, for people with osteoarthritis, according to a review of previous trials. “We had a systematic review for Cochrane from 2008 and 2009, but there were much less articles,” said Dr. Martin Van der Esch, who coauthored…
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