Two Phase 3 trials have shown that epratuzumab did not meet its primary endpoints for treating SLE. Meanwhile, a Phase 3 study has shown adalimumab is effective for treating enthesitis-related arthritis in juveniles…
FDA Warns Makers of Superbug-Prone Scopes over Testing Violations
(Reuters)—Manufacturers of duodenoscopes linked to recent superbug outbreaks at U.S. hospitals skirted a host of testing, manufacturing and reporting requirements, the U.S. Food and Drug Administration said in warning letters to the companies released on Monday. The letters, sent on Aug. 12, cite Olympus Corp Pentax Medical and Fujifilm Holdings Corp with multiple violations found…
Patients Don’t Realize Smoking Worsens Inflammatory Bowel Disease
(Reuters Health)—Doctors know smoking can increase the risk for certain common inflammatory bowel diseases (IBD), but many patients haven’t gotten the message, a new study suggests. Out of 239 patients with two common types of IBD (Crohn’s disease and ulcerative colitis) only half were aware of the smoking risks associated with these conditions. “The take-home…
Nuclear Medicine Exposures Up Health Risks for Radiology Techs
NEW YORK (Reuters Health)—Technologists working in nuclear medicine have a heightened risk for some cancers and myocardial infarction, according to a nationwide U.S. survey led by National Cancer Institute (NCI) researchers. “Our results were mainly driven by exposures occurring before 1980, which is consistent with evidence that most cancers and other serious radiation-related chronic disease…
Similar RA Outcomes with Abatacept & Tocilizumab
NEW YORK (Reuters Health)—Clinical outcomes of rheumatoid arthritis (RA) are similar with abatacept and tocilizumab treatment, but the factors that predict efficacy differ for the two agents. “The recommendations for RA treatment from the U.S. and EU describe the use of abatacept and tocilizumab as first-line biologics along with anti-TNF (anti-tumor necrosis factor) inhibitors,” Dr….
Intensive Program Relieves Symptoms of Juvenile Fibromyalgia
Pain can be reduced and functionality significantly improved for children with fibromyalgia without drug therapy, according to a study of 64 children in Philadelphia. Researchers combined intensive physical therapy and psychotherapy in individualized programs to treat the fibromyalgia patients…
Knee Replacement May ‘Turn Back the Clock’ for Arthritis Pain
(Reuters Health)—Knee replacement surgery may significantly ease pain and improve leg function and quality of life in patients with osteoarthritis or rheumatoid arthritis (RA), a new study suggests. While surgery doesn’t restore the same level of comfort and function patients had in their younger years, before they developed arthritis, the authors write in the journal…
GSK Shuts U.S. Plant Due to Bacteria
(Reuters)—Drugmaker GlaxoSmithKline temporarily closed a North Carolina factory on Tuesday after testing at a cooling tower found bacteria that causes deadly Legionnaire’s disease. The Legionella bacteria were discovered during routine inspections at the site in Zebulon, N.C., the company said. The shutdown is not expected to disrupt supplies of medicines made at the factory, which…
High-Risk Medical Devices Backed by Few Studies
(Reuters Health)—Many high-risk therapeutic devices get U.S. Food and Drug Administration (FDA) approval with only one study proving their safety and efficacy before going to market. Studies of how the devices work once they are on the market are also few and far between, according to a new study that looked at all 28 high-risk…
Rude Comments Damage Medical Team Performance
NEW YORK (Reuters Health)—Medical practitioners’ performance suffers when they are exposed to rudeness, new findings show. Neonatal intensive care unit (NICU) team members who heard disparaging comments while participating in a simulation exercise had lower diagnostic and procedural performance scores compared to team members who didn’t hear rude comments, Dr. Arieh Riskin, of Bnai-Zion Medical…
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