(Reuters)—Closer coordination between healthcare facilities and public health departments could save 37,000 U.S. lives over five years by preventing infections from antibiotic-resistant germs and from Clostridium difficile, according to a government report released on Tuesday. Germs that no longer respond to antibiotics cause more than 2 million illnesses and 23,000 deaths each year in the…
Brentuximab Vedotin Enters Phase 2 Trials & More
Phase 2 clinical trials have begun to assess the safety of brentuximab vedotin for the treatment of SLE. Also, the FDA is reviewing an application for a once-daily tofacitinib citrate tablet to treat RA…
New Analysis Underscores Improving Pharma R&D Productivity
LONDON (Reuters)—Drug industry productivity is continuing to improve, with a bumper haul of new products being launched and companies proving more successful in the final stages of clinical testing, according to a new analysis. Data from Thomson Reuters published on Tuesday showed the number of innovative medicines, or new molecular entities, launched globally in 2014…
China to Expand Medical Insurance for Major Illnesses
BEIJING (Reuters)—China will expand medical insurance to cover all critical illnesses for all urban and rural residents by the end of the year, the cabinet said on Sunday, the latest step in a plan to fix a healthcare system that has sparked public discontent. The State Council said 50% of the medical costs will be…
Infection & Hospitalization in SLE
From 1996–2011, the rates of hospitalization due to serious infectious diseases in patients with systemic lupus erythematosus (SLE) increased substantially, according to new research. In a retrospective data-driven study, researchers plotted and compared hospitalization and in-hospital mortality rates of SLE and non-SLE populations, determining the trends for the five most common infections…
Varicella Zoster Virus May Cause Giant Cell Arteritis
Researchers have recently discovered a connection between the varicella zoster virus infection, which causes chicken pox and shingles, and giant cell arteritis…
CareFirst Sees More Than Doubled Savings on Shared Rewards with Doctors
(Reuters)—Insurer CareFirst BlueCross BlueShield said on Thursday its cost savings on providing healthcare rose sharply last year in a program that rewards doctors for keeping patients out of the hospital. The non-profit health insurer operates an approach to delivering care that emphasizes coordination among providers, led by a patient’s primary care physician. The model is…
Skin Complications of Anti-TNF Therapy Common in IBD
NEW YORK (Reuters Health)—Dermatologic complications hit about one in five patients with inflammatory bowel disease (IBD) on anti-tumor necrosis factor (anti-TNF) therapy, leading to discontinuation of treatment, a French study finds. Dr. Laurent Peyrin-Biroulet, from University Hospital of Nancy, and colleagues note that dermatological complications of anti-TNF therapy are known to occur frequently in IBD…
Maintaining Board Certification Has High Hidden Cost
NEW YORK (Reuters Health)—The American Board of Internal Medicine (ABIM) maintenance-of-certification (MOC) program could cost $5.7 billion in physicians’ time and fees over the next decade, according to a new model study. “We estimate that physicians will spend 33 million hours over 10 years to fulfill MOC requirements,” Dr. Dhruv S. Kazi from the University…
Adalimumab Remains Safe, Effective for Psoriasis
NEW YORK (Reuters Health)—In adults with chronic plaque psoriasis, adalimumab (Humira, AbbVie) was generally well tolerated and effective during five years of therapy, according to a new analysis. The interim analysis is from ESPRIT, a 10-year multinational post-marketing registry. “Clinical trials are not the real world,” in part because patients with comorbidities are screened out…
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