Researchers show, for the first time, that small fiber function and morphology is impaired in patients with fibromyalgia. (posted June 18, 2013)
Th17 May Contribute to Bone Destruction by Modifying Osteoclasts
New research describes the role of RANKL-expressing Th17 cells in inflammatory bone destruction. (posted June 3, 2013)
TNF-α Impairs Regulatory T Cells in Patients with Rheumatoid Arthritis
When researchers treated patients with RA with TNF-α–specific antibody, they were able to restore Treg cell function. (posted June 3, 2013)
Salt as a Promoter of Th17 Cells and Autoimmune Disease
New research on Th17 suggests that a high salt diet may be a risk factor for inflammation.
Will New Rheumatoid Arthritis Blood Test Improve Early Diagnosis?
Two new blood tests may boost the accuracy of RA diagnose, although more data needed. (posted May 5, 2013)
Steroid Injections for Lateral Epicondylalgia Worse than Placebo in Long Term
In a recent study of unilateral lateral epicondylalgia, corticosteroid injection resulted in worse clinical outcomes compared to placebo injection, and there were no significant differences in those who received physical therapy or no physical therapy.
Chondrocyte Enlargement Sheds New Light on Cell Volume Regulation
New research describes the regulation of skeletal size and explores how cells sense, modify, and establish a volume set point.
Large Genome Study Identifies Genetic Risk Factors for Gout
Researchers have identified 28 genome-wide significant urate concentration–associated loci, underscoring the importance of metabolic control in urate production.
Susceptibility Loci Shed Light on Fundamental Pathways of Psoriasis
Investigators have described 15 new psoriasis susceptibility loci. The loci highlight the importance of the skin in both acquired and innate host defense and identify the innate immune response as a key factor in psoriasis.
Sequester Affects Rheumatologists on Two Fronts—Medicare Reimbursement and Research Funding
Rheumatologists are already feeling two effects from Congress’ inability to solve sequestration: a 2% reduction in Medicare reimbursements and slashed funding for research financed by the National Institutes of Health.
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