LONDON (Reuters)—U.S. drug approvals hit a 21-year high in 2017, with 46 novel medicines winning a green light—more than double the previous year—while the figure also rose in the European Union. The European Union (EU) recommended 92 new drugs, including generics, up from 81; and China laid out plans to speed up approvals in what…
Pedometers & RA: Does Increasing Physical Activity Decrease Fatigue?
Recent research examined the effectiveness of a pedometer-based intervention for managing fatigue in patients with rheumatoid arthritis (RA). During the 21-week trial, RA patients using pedometers successfully increased their physical activity, with a greater than 30% decrease in the proportion of participants classified as sedentary. Patients also decreased their reported fatigue, and some reported improvements in function, pain, depressive symptoms and disease activity levels…

Etanercept’s New Autoinjection System; Plus FDA Approves Ixekizumab for Active PsA
In the U.S., a new formulation and an ergonomic delivery system for single doses of etanercept are now available for RA patients…
Many Doctors & Specialists Don’t Adhere to Fibromyalgia Diagnostic Criteria
NEW YORK (Reuters Health)—Generalist doctors, and even many specialists, have relatively poor knowledge of the American College of Rheumatology 1990 and 2010 fibromyalgia diagnostic criteria, according to results of a survey conducted in Canada. “Physicians do not have adequate and homogeneous knowledge of the fibromyalgia diagnostic criteria. Approximately half of physicians did not adhere to…
Vitamin D, Calcium Supplements May Not Lower Fracture Risk
(Reuters Health)—Older adults who take vitamin D and calcium are no less likely to break their hips or other bones than peers who don’t use these supplements, a research review suggests. Researchers examined data from 33 previous trials with a total of more than 51,000 people aged 50 or older who were living in the…
Updated Obamacare Enrollment Figure Dips to 8.7 Million
(Reuters)—About 8.7 million people enrolled in healthcare plans for 2018 using the federal Obamacare marketplace, according to updated government figures released on Thursday. The number represented a slight decline from the 2017 enrollment figure when about 9.2 million people signed up for health insurance policies from private insurers on the HealthCare.gov platform. It was slightly…

A Defect in Mitochondrial Function May Underlie Chronic Fatigue Syndrome
The peripheral blood mononuclear cells (PBMCs) of patients with chronic fatigue syndrome (CFS) may be unable to meet certain energetic demands, according to a U.K. study. Researchers found that PBMCs in healthy individuals may adapt to environmental stressors by enhancing their ability to increase ATP production through mitochondrial respiration, but not in patients with CFS…

Developing & Leading a Research Team
Translational research is designed to investigate a particular disease process to achieve an improved outcome for patients. Here are some insights into how to bring together the right people for a research team and keep that team focused…
U.S. Official Says 8.8 Million People Signed Up for 2018 Obamacare Health Plans
NEW YORK (Reuters)—About 8.8 million people signed up for 2018 Obamacare health insurance plans on the federally run HealthCare.gov, a top U.S. health official said on Thursday, about a 4 percent decline from sign-ups for 2017. The Twitter post from Seema Verma, the head of the Centers for Medicare and Medicaid Services, did not provide…
U.S. Life Expectancy Fell in 2016 as Opioid Overdoses Surged—CDC
NEW YORK (Reuters)—Life expectancy in the United States dipped in 2016 as the number of deaths due to opioid drug overdoses surged and total drug overdose deaths rose 21% to 63,600, the U.S. Centers for Disease Control and Prevention said on Thursday. Life expectancy fell to 78.6 years, a decrease of 0.1 year from 2015,…
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