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Urate-Lowering Therapy in the Treatment of Patients with Chronic Kidney Disease

Summarized from The New England Journal of Medicine  |  

CKD-FIX Elevated serum urate levels are associated with progression of chronic kidney disease (CKD). In the CKD-FIX study, a randomized, controlled trial, Badve et al. set out to determine whether urate-lowering treatment with allopurinol can attenuate the decline of the estimated glomerular filtration rate (eGFR) in patients with chronic kidney disease  at risk for progression.1…

Key Research in Axial Spondyloarthritis Encapsulated

David S. Pisetsky, MD, PhD  |  

Our understanding of (axSpA) has really changed, especially with regard to male-female differences. In this report, we identify important research on axSpA presented at ACR Convergence 2024, summarize the abstracts and comment on why each is important, addressing the relevance for clinicians and the potential impact on future research.

Are Sacroiliac Joint MRIs Accurate in Routine Clinical Practice?

Anna E.F. Hadsbjerg, Simon Krabbe, Nora Vladimirova, Adrian Ciurea, Kristyna Bubova, Monika Gregová, Michael Nissen, Burkhard Moeller, Raphael Micheroli, Susanne Pedersen, Jakub Zavada, Ziga Snoj, Karlo Pintaric, Bjorn Gudbjornsson, Ziga Rotar, Iris Eshed, Iwona Sudol-Szopinska, Kasper Gosvig, Torsten Diekhoff, Robert Lambert, Manouk de hOoge, Helena V.G. Elmo, Merete Hetland, Lykke Oernbjerg & Mikkel Ostergaard  |  

Hadsbjerg et al. compared assessments of sacroiliac joint MRIs in local MRI reports from routine care in five European countries with re-reads by central experts in patients with a diagnosis of axial spondyloarthritis (axSpA) or psoriatic arthritis (PsA) to estimate the extent of over- or under-reporting of features and misclassification.

Top Research in Psoriatic Arthritis Presented at ACR Convergence 2024

David S. Pisetsky, MD, PhD  |  

Editor’s note: What research on psoriatic arthritis (PsA) presented at ACR Convergence 2024 has the greatest potential for a positive impact on clinical care, treatment options or serve as the basis for future research? That’s the question The Rheumatologist asked David S. Pisetsky, MD, PhD—our founding editor—to consider. Dr. Pisetsky, a professor of medicine and immunology…

Systemic Lupus Erythematosus: A Complex, Multi-Challenging Disease

Graciela S. Alarcón, MD, MPH, MACR  |  

Reviewing the research presented at ACR Convergence 2024 WASHINGTON, D.C.—Despite significant advances that have taken place over the past several years, systemic lupus erythematosus (SLE) still presents great challenges to rheumatologists, given its unpredictable clinical course and the eventual consequences the disease itself and the complexity of its treatments impose on individual patients, their families…