Focus Rheums| ACR Convergence 2024 Previews

An official publication of the ACR and the ARP serving rheumatologists and rheumatology professionals

Polymyositis-Dermatomyositis Tied to Arrhythmias in Young, Middle-Aged Adults

Lisa Rapaport  |  

“Given the supposed key role of inflammatory activation in the pathogenesis of arrhythmias, lowering the inflammatory burden through an increasingly tight control of disease activity may represent the most effective intervention to reduce arrhythmic risk in these patients,” Dr. Lazzerini, who wasn’t involved in the study, says by email.

“Intriguingly, these considerations could be more generally applicable to all the diseases characterized by chronic systemic inflammation and could help elucidate the link between subclinical low-grade chronic inflammation and arrhythmic risk in apparently healthy individuals of the general population,” Dr. Lazzerini says.

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Reference

  1. Naaraayan A, Meredith A, Nimkar A, et al. Arrhythmia prevalence among patients with polymyositis-dermatomyositis in the United States: An observational study. Heart Rhythm. 2021 May 26;S1547-5271(21)00456-2. Online ahead of print.

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