MRI is a potentially powerful tool to identify proteoglycan and collagen loss, both possibly meaningful changes seen early after joint injury.
“We have to prevent collagen loss, because that occurs early on. There is a narrow window, but I think we can prevent a lot of the OA afterward,” he concluded. Proteomic analysis may tell us about gene markers that predict who is likely to develop post-traumatic OA after surgery and reveal more clues on why some people resolve their inflammation while others do not.
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Susan Bernstein is a freelance medical journalist based in Atlanta.
References
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