While a controlled study is needed with RA patients to make more definitive recommendations, these results suggest that transdermal fentanyl should be considered as a treatment option for RA patients who are not experiencing a reduction in pain intensity to allow participation in daily and social activities. Providers should remember that the effectiveness of opioids varies with the individual and the type of opioid, as well as the dose. Furthermore, some time may be necessary to establish the best treatment plan. An attractive feature of transdermal fentanyl is that it can used in combination with other agents.
References:
- Auret K, Schug, SA. Underutilisation of opioids in elderly patients with chronic pan: approaches to correcting the problem. Drugs Aging. 1998;22:641-654.
- American Pain Society. Guideline for the Management of Pain in Osteoarthritis, Rheumatoid Arthritis, and Juvenile Chronic Arthritis. Glenview, Il: 2002, p. 81.