Shorter Antibiotic Therapy Effective for Pyogenic Vertebral Osteomyelitis

The study investigators appear to agree with this point. They specify that results are valid for older patients (≥ 75 years), and those with severe infection. They caution, however, against extrapolating the findings of their study to patients with other vertebral osteomyelitis due to non-pyogenic microorganisms, methicillin-resistant Staphylococcus aureus, or those without microbiological identification. (posted 1/16/15)

Lara C. Pullen, PhD, is a medical writer based in the Chicago area.

References

1. Bernard L, Dinh A, Ghout I, et al. Antibiotic treatment for 6 weeks versus 12 weeks in patients with pyogenic vertebral osteomyelitis: an open-label, non-inferiority, randomised, controlled trial. 2014. Lancet. Nov. 4. doi:10.1016/S0140-6736(14)61233-2. [Epub ahead of print].

2. Lora-Tamayo J and Murillo, O. Shorter treatments for vertebral osteomyelitis. 2014. Lancet. Nov. 5. doi:10.1016/S0140-6736(14)61936-X. [Epub ahead of print].

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