In response to these limitations, the ASDAS-CRP and ASDAS-ESR composite instruments were created and offer two formulas—a preferred, with C-reactive protein (CRP), and alternative, with erythrocyte sedimentation rate (ESR)—to score disease activity, with cutoffs for disease activity states, representing the status of disease, and cutoffs for change scores, representing response levels to treatment.
Mary Beth Nierengarten is a freelance medical journalist based in Minneapolis.