Treatment with ticagrelor was associated with a 29% lower risk of developing OA than treatment with clopidogrel over five years of follow-up. Baker et al. hypothesize the reduction in OA seen in patients who received ticagrelor may in part be due to increased extracellular adenosine levels.
Refer to the full study for all source material.
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Excerpted and adapted from:
Baker MC, Weng Y, Robinson WH, et al. Reduction in osteoarthritis risk after treatment with ticagrelor compared to clopidogrel: A propensity score matching analysis. Arthritis Rheumatol. 2020 Nov;72(11).