Dr. Powell, who conducts research in the field, added that the current study “supports this theory by demonstrating that compromised intestinal barrier function and a pre-existing inflammatory condition can enhance the uptake of, and/or pathological response to, titanium dioxide particles. Interestingly, this and other work also show that titanium dioxide particles can be absorbed, at least to some extent, into the circulation, and the implications of both this and the potential to aggravate intestinal responses deserve careful further scrutiny—most especially by the regulators of food additives and excipients given that the particles have no essential function in these uses.”
The Swiss Philanthropy Foundation, the Swiss National Science Foundation, and the Swiss IBD Cohort supported this research. The authors made no disclosures.