Focus Rheums| ACR Convergence 2024 Previews

An official publication of the ACR and the ARP serving rheumatologists and rheumatology professionals

Varicella Zoster Virus Downregulates Programmed Death & Promotes Inflammation

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They also suggest that such a detailed understanding of how inflammation can persist in the absence of effective viral clearance may be useful in the identification of targeted therapy of VZV-induced disease.

Lara C. Pullen, PhD, is a medical writer based in the Chicago area.

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Reference

  1. Jones D, Blackmon A, Neff CP, et al. Varicella zoster virus downregulates programmed death ligand 1 and major histocompatibility complex 1 in human brain vascular adventitial fibroblasts, perineurial cells and lung fibroblasts. J Virol. 2016 Sep 14. pii: JVI.01546-16. [Epub ahead of print]

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