Ankylosing spondylitis primarily affects the joints and ligaments of the spine, but may also have an impact on other joints. Patients experience pain and stiffness that limit mobility in the back and other affected joints. Symptoms can come and go, last for long periods of time and be severe. Anti-tumor necrosis factor (anti-TNF) drugs are…
Lara C. Pullen, PhD, is a medical writer with a PhD in microbiology/immunology from Northwestern University’s Feinberg School of Medicine. As a medical writer she has covered topics as diverse as diabetes, cardiovascular disease, and autism. Her favorite subject, however, is the role of the immune system in health and disease. Dr. Pullen is also the mother of three children, the youngest of whom has Prader-Willi Syndrome (PWS). She is an active member of the PWS community and a thought leader on the importance of the ketogenic diet for this patient population.
Articles by Lara C. Pullen, PhD
Progress Made in Search for a Fibromyalgia Biomarker
Fibromyalgia syndrome (FMS), rheumatoid arthritis (RA) and spondyloarthritis (SpA) all exhibit multifaceted manifestations, and many patients exhibit overlapping comorbidities. However, patients with FMS are distinct from others in that they experience widespread pain, fatigue and mood changes, including anxiety and depression. Although its hallmark symptom of pain causes rheumatologists to consider FMS a pain disorder,…
Complement Polymorphism Plays Role in RA Pathology
Study proposes increased active C5a recruits neutrophils to arthritic joints to maintain inflammation
Atherosclerosis Insights May Shed Light on Lupus
New research compares pathogenic immune response in SLE with immune response that contributes to atherosclerotic plaque
Infliximab, Tocilizumab Can Help in Large Vessel Vasculitis
Case studies show some patients with LVV can achieve remission after treatment with biological agents
Atherosclerosis, Cardiovascular Disease More Common in Patients with Primary Sjögren’s Syndrome
Study adds to research linking increased risk of morbidity, early mortality from CV events among patients with systemic autoimmune diseases
Rat Model of Arthritis Sheds Light on How Disease Affects Bone
Increased bone turnover, mineral loss among signs of bone damage found in disease-induced rats
Metabolic Biosensor Implicated in Gout
AMP-activated protein kinase may be link between nutritional excess, inflammation that leads to gout
New Compound Promotes Recovery from Spinal Cord Injury
Research suggests delivery of protein peptide can restore serotonergic innervation to spinal cord below level of injury; facilitate recovery of locomotor and urinary system function
Hepatitis C Virus Infection Associated with Rheumatoid Arthritis
Research finds patients with chronic HCV infection more likely to develop RA, especially men
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