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Lara C. Pullen, PhD

Lara C. Pullen, PhD, is a medical writer with a PhD in microbiology/immunology from Northwestern University’s Feinberg School of Medicine. As a medical writer she has covered topics as diverse as diabetes, cardiovascular disease, and autism. Her favorite subject, however, is the role of the immune system in health and disease. Dr. Pullen is also the mother of three children, the youngest of whom has Prader-Willi Syndrome (PWS). She is an active member of the PWS community and a thought leader on the importance of the ketogenic diet for this patient population.

Articles by Lara C. Pullen, PhD

ADA2 Mutation Connects Vascular Pathology to Immunodeficiency

Lara C. Pullen, PhD  |  June 13, 2014

Two new studies that examine the effects of a genetic defect in adenosine deaminase 2 may advance a gene-based definition of vasculopathy

Treg Cells May Orchestrate Muscle Repair after Injury

Lara C. Pullen, PhD  |  May 30, 2014

New research shows the accumulation of regulatory T cells in damaged muscle corresponds with a switch in the myeloid cell infiltrate from a proinflammatory to a proregenerative phenotype.

Skin Oils Act as Natural, Tissue-Specific Autoantigens

Lara C. Pullen, PhD  |  May 2, 2014

The results of this study identify natural lipids present in the skin that augment and inhibit human T cell response, supporting the idea that lipids are T cell antigens.

Understanding the Role of Citrullination in Rheumatoid Arthritis

Lara C. Pullen, PhD  |  April 28, 2014

Activation of peptidylarginine deiminases during complement and perforin activity may be at the core of citrullinated autoantigen production in RA.

Can Scleroderma Be Cured by Curing Cancer?

Lara C. Pullen, PhD  |  March 31, 2014

Research review

Human RNAi Therapy Jumps Hurdle

Lara C. Pullen, PhD  |  February 20, 2014

A new proof-of-concept human study brings RNA interference therapy one step closer to market.  (published March 3, 2014)

Microbiome Research Provides Clue to Rheumatoid Arthritis

Lara C. Pullen, PhD  |  February 20, 2014

A new study suggests that intestinal expansion of Prevotella copri may be associated with the pathogenesis of RA

Interleukin 1-alpha Is Critical for Establishment of Inflammatory Lung Disease

Lara C. Pullen, PhD  |  January 21, 2014

New research clarifies the role of fibroblasts in chronic lung disease.  (posted Jan. 21)

Does Anti-Tumor Necrosis Factor-Alpha Increase Cardiovascular Burden?

Lara C. Pullen, PhD  |  January 14, 2014

Long-term use of TNFα inhibitors in patients with rheumatoid arthritis and ankylosing spondylitis is associated with both gains in fat mass and a shift in fat mass to the visceral region.  (posted Jan. 14)

Genetic Link Between Cellular Cholesterol Homeostasis and Energy Metabolism

Lara C. Pullen, PhD  |  November 19, 2013

A new study suggests that GATM may serve as the functional link between the ability of statins to lower cholesterol and their ability to cause statin-induced myopathy.   (posted Nov. 19)

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