The makers of FX006, a steroid injection for treating pain in patients with knee osteoarthritis, have submitted a new drug application to the FDA…
Does Telephone Coaching Enhance Physical Activity Programs?
Health coaching by telephone is increasingly being used to assist in chronic disease self-management. A recent study examined the benefits of simultaneous health coaching via telephone as an addition to a physiotherapist-prescribed home-based physical activity program for patients with knee OA. Although participants receiving additional coaching had a short-term improvement in adherence, changes in pain and function did not differ between the study’s groups at six months…
Low Levels of Vitamin D3 May Increase OA Pain
In a study of patients with knee osteoarthritis (OA), researchers found that the cytokine IL-17A may play a role in the pain associated with the disease. Specifically, decreased serum levels of vitamin D3 may contribute to OA pain via the regulation of immune responses…
A New Approach to Fracture Prevention
Glucocorticoids are widely prescribed by rheumatologists, and the effects of daily and cumulative doses of these drugs on bone mineral density (BMD) are important elements of a draft clinical guideline document presented on Nov. 13 at the 2016 ACR/ARHP Annual Meeting in Washington, D.C. Leaders of the ACR guideline project discussed their recommendations at the…
New Insights into the Structure of Collagen Fibril
A study of knee and hip articular cartilage found that thick fibers were bundles of thin fibrils—like a multi-thread rope in which each thread corresponds to a prototypic sub-fibril. The organization of the fibers also differed between the cartilages of distinct tissues, which may explain how a breakdown in the fiber pattern contributes to pathology…
Patients with Parkinson’s Disease Are at Risk for Carpal Tunnel Syndrome
Patients with Parkinson’s disease may be at risk of carpal tunnel syndrome (CTS). New research examined why patients with Parkinson’s have a higher incidence of CTS than that of the general population. The study found that those patients who underwent subthalamic nucleus deep brain stimulation to monitor them for neuropathy may develop CTS…
Treating the Athlete: New Thoughts on How to Prevent & Treat Arthritis in Athletes & Raise Their Awareness
All athletes—amateur and professional—should understand their risks for developing injury-related arthritis. Rheumatologists and other physicians at the Hospital for Special Surgery in New York take a rapid approach to treating athletes, often considering intense physical therapy, innovative treatments and surgery much sooner than for the average patient—all to keep joints healthy and enable athletes to play for as long as possible…
SSRIs Act Centrally to Cause Bone Loss
In a recent study, investigators examined the effects of both the short- and long-term use of selective serotonin-reuptake inhibitors (SSRIs) on the development and loss of bone. The study results describe the mechanisms by which SSRIs, specifically fluoxetine, affect osteoclasts short term to increase bone mass, but also how the treatment may cause bone loss at six weeks in mice…
Can Nasal Tissue Be Used to Repair a Damaged Knee Joint?
(Reuters Health)—Doctors might one day be able to harvest cells from patients’ noses to produce cartilage that can be transplanted into damaged knee joints, a small experiment suggests. Because the experiment only included 10 adults who were followed for just two years, it’s impossible to say for sure whether this procedure would be safe or…
New Treatment Guidelines to Be Presented at the 2016 ACR/ARHP Annual Meeting
Two sets of guidelines—one on managing anti-rheumatic drugs perioperatively for patients undergoing total hip and knee replacements, and another that updates glucocorticoid-induced osteoporosis prevention and treatment strategies—will be featured in sessions at the 2016 ACR/ARHP Annual Meeting this month. The Sessions Sunday, Nov. 13, 2:30–3:30 p.m.: Glucocorticoid-Induced Osteoporosis Prevention and Treatment: A New ACR Clinical…
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