Patients with anti-neutrophil cytoplasmic antibody–associated vasculitides (AAV) have an increased risk of mortality. But treatments have evolved in recent years. Recent research found that between 1999 and 2017 the AAV mortality rate declined by nearly 2% per year in patients 65–74 years old…
Depression in Ankylosing Spondylitis: Mastery Is Key
A recent study indicates that depression in patients with ankylosing spondylitis is a result of both contextual and disease-related factors. Researchers found a patient’s mastery—the perception they have control over things in their lives—plays a key role in the development of depression in this patient population…
Beyond Drugs: ACR/AF Guideline Update for Hand, Knee & Hip OA Emphasizes Exercise
Guideline authors discussed therapeutic options for patients with hand, knee and hip OA in a session at the 2019 ACR/ARP Annual Meeting.
Pegloticase & Methotrexate Combination Therapy May Benefit Patients with Uncontrolled Gout
Patients with uncontrolled gout may benefit from a combination of pegloticase and methotrexate therapy, according to a small, retrospective study…
Myositis Autoantibodies: A Comparison of Serotyping Panels
The challenges of diagnosing myositis are numerous, with many tests resulting in false positives and negatives for autoantibody levels. Researchers recently compared a line blot array currently being used in research with the Oklahoma Medical Research Foundation Myositis panel, which is used in clinical testing. They found some patients were positive according to the research test, but negative according to the clinical test…
ACR Publishes Disease Activity and Functional Status Assessment Measure Recommendations for RA
The recommendations include updated disease activity measures and a new set of functional status assessment measures for rheumatoid arthritis.
Nailfold Videocapillaroscopy Provides a Window into Inflammatory Myopathies
A recent study investigated the possible differences in nailfold videocapillaroscopy in four types of inflammatory myopathies. Researchers observed giant capillaries, disorganization and major capillary loss in dermatomyositis and overlap myositis patients, finding dermatomyositis and overlap myositis imaging was different from that of antisynthetase syndrome and immune-mediated necrotizing myopathy…
Potential Link Between OA & Gout
Monosodium urate (MSU) crystal formation, deposition and gout flares frequently affect joints that have been damaged or are affected by osteoarthritis. These researchers examined the effects of human cartilage homogenates on MSU crystallization and MSU crystal-induced inflammation…
Tildrakizumab Promising for Psoriasis in Patients with PsA
New research shows tildrakizumab may significantly improve psoriasis in patients with active psoriatic arthritis…
New Consensus Recommendations Guide Sjögren’s Syndrome Management
NEW YORK (Reuters Health)—New consensus-based recommendations from the European League Against Rheumatism (EULAR) address the management of Sjögren’s syndrome with topical and systemic therapies. Sjögren’s syndrome presents with a broad spectrum of clinical manifestations and autoantibodies, including antinuclear antibodies (the most frequently detected), anti-Ro/SS-A (the most specific) and cryoglobulins and hypocomplementemia (the main prognostic markers)….
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