NEW YORK (Reuters Health)’Over the last three decades, there has been a significant decline in the incidence of rheumatoid factor (RF) positive rheumatoid arthritis (RA), while the overall incidence of RA has remained about the same, researchers report. “These trends may suggest changing serological profile of RA over time which may have implications for RA…
How Autoimmune & Non-Autoimmune Family Conditions Predict Rheumatoid Arthritis
New research has incorporated confounders, such as smoking, to build a clearer picture of family-related factors that may help predict who will develop rheumatoid arthritis…
As Lyme Disease Spreads Across the U.S., Stay Alert for Fatal Lyme Carditis
The reach of Lyme disease is expanding across the U.S., and cases may be under-reported. A recent CDC case report describes the experiences of two patients with fatal cases of Lyme carditis…
A Combined Immunosuppressive Regimen for ILD MDA5-Positive Dermatomyositis
Interstitial lung disease accompanied by anti-melanoma differentiation-associated gene 5 positive dermatomyositis is often rapidly progressive and associated with poor prognosis. In this study, a combined immunosuppressive regimen of high-dose glucocorticoids, tacrolimus and intravenous cyclophosphamide proved more effective than treatment with high-dose glucocorticoids and stepwise addition of an immunosuppressant in a historical control group.
Can Lupus Be Prevented? Research Reveals Clues to Who’s Most Likely to Transition to Classified Disease
How does a patient transition from health to active SLE? This question is the crux of the research conducted by Judith A. James, MD, PhD, and colleagues…
Sodium-Glucose Cotransporter-2 Inhibitors May Decrease Gout Risk in Some Patients
Recent research assessed the risk of gout in patients with type 2 diabetes mellitus prescribed sodium-glucose cotransporter-2 (SGLT2) inhibitors compared with those prescribed a glucagon-like peptide-1 (GLP-1) agonist. The study found patients on the SGLT2 inhibitor had a lower rate of gout, suggesting SGLT2 inhibitors may actually reduce the risk of gout among this patient population…
5 Challenges in the Treatment & Diagnosis of Lupus
A recent study published in Lupus Science & Medicine lays out five of the top barriers impeding progress in lupus diagnosis and treatment.1 The Addressing Lupus Pillars for Health Advancement project (ALPHA), led by the Lupus Foundation of America (LFA), researchers at the Tufts School of Medicine Center for the Study of Drug Development (Tufts…
How to Diagnose Upper Extremity Injuries
ATLANTA—Two ways to investigate injuries to the upper extremities are by in-depth physical examinations and ultrasound. In a Clinical Practice session at the 2019 ACR/ARP Annual Meeting, Anatomy: Correlating Physical Exam and Ultrasound in Common Sports Injuries of the Upper Extremity, Carlin Senter, MD, FACP, associate professor of primary care sports medicine at the University…
From Chronic Low Back Pain to Axial Spondyloarthritis
ATLANTA—Research into possible genetic drivers of the axial spondyloarthritis (axSpA), including the role of the genetic marker HLA-B27, is advancing, John D. Reveille, MD, professor and vice chair of medicine at the University of Texas McGovern Medical School, Houston, told attendees at the 2019 ACR/ARP Annual Meeting. Dr. Reveille delivered the Philip Hench, MD, Memorial…
Study Finds an Indirect Association Between Sleep & Inflammation
In a study in Arthritis Care & Research, researchers showed an indirect association between osteoarthritis (OA) and sleep health in older men.1 In those participants with OA, the condition is associated with poorer sleep health, as well as a 16% higher incidence of elevated C-reactive protein and 12% higher odds of having elevated interleukin 6….
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