The FDA has approved subcutaneous tocilizumab for treating active systemic juvenile idiopathic arthritis in pediatric patients as young as 2 years old…
Central Sensitization to Pain May Not Predict Long-Term Outcomes after Carpal Tunnel Release Surgery
Pain sensitization, such as that experienced by patients with carpal tunnel syndrome (CTS), has been associated with poorer clinical outcomes after surgery. New research has found that, although pain sensitization in CTS patients correlates with preoperative symptom severity, CTS symptoms did not have a persistent effect on functional outcomes after surgery…
Tennis-Wozniacki Reveals Battle with Rheumatoid Arthritis
SINGAPORE (Reuters)—Australian Open champion Caroline Wozniacki has opened up about her battle with rheumatoid arthritis, saying there have been days this year when she found it hard to get out of bed. The Dane, who claimed her maiden Grand Slam title in Melbourne this year, crashed out of the WTA Finals in the group stage…
Uveitis: Know the Risk Factors, Symptoms & Treatment Options
Inflammatory diseases can cause uveitis. Early detection and treatment are essential, but when uveitis goes undetected it can cause blindness. Here’s how to protect your patients…
Are Bending & Lifting Associated with Lumbosacral Radiculopathy Syndrome?
Patients with lumbosacral radiculopathy syndrome (LRS) may wonder if physicality of their jobs contributed to the development of their symptoms. A recent systematic review sought to identify LRS work-related risk factors. Researchers found that bending and lifting of the trunk, both alone and in combination, may contribute to LRS…
Trimethoprim-Sulfamethoxazole Prophylaxis Reduced Rituximab Infection Risk
Severe infections occurred in 25% of patients with anti-neutrophil cytoplasm antibody (ANCA) associated vasculitis (AAV) who were treated with rituximab, according to results of an observational study conducted in the United Kingdom (U.K.) and Austria. Trimethoprim-sulfamethoxazole (TMP/SMX) prophylaxis, however, reduced the risk of severe infections, the investigators reported in Annals of the Rheumatic Diseases.1 Andreas…
2 Markers May Help Predict Who will Progress to Sjögren’s
Physicians already know a great deal about Sjögren’s syndrome’s symptoms and potential complications, and a new study confirms data on two long-suspected predictors of progression (i.e., measurable phenotypic findings) that could show which patients are likely to progress to active disease: hypergammaglobulinemia and hypocomplementemia. Published in the February issue of Arthritis Care & Research, “Natural…
Antibodies Against Oxidized Phospholipids Protect Against Osteoporosis
It has long been known that hyperlipidemia adversely affects bone, but the exact pathologic mechanism(s) underlying hyperlipidemia-induced bone loss has not been fully understood. Until now. Pathogenesis of Osteoporosis New research by Ambrogini and colleagues shows that oxidation-specific epitopes derived from lipid peroxidation contribute to the pathogenesis of osteoporosis.1 Importantly, the research shows that innate…
Fighting Lupus Among Latinas
Systemic lupus erythematosus (SLE) is more prevalent among Hispanic women than white women, according to two recent studies published in Arthritis & Rheumatology.1,2 However, Latinas often lack awareness of lupus, which can contribute to delays in diagnosis and treatment, and lead to worse outcomes. “One of the challenges is reaching out to the Latino community,…
Permanent Vision Loss in Late Giant Cell Arteritis
Patients with polymyalgia rheumatica (PMR) or peripheral arthritis may require extra vigilance during treatment because of a suspected link to giant cell arteritis (GCA) and, potentially, permanent vision loss. “Development of giant cell arteritis after treating polymyalgia or peripheral arthritis: a retrospective case-control study,” a March 2018 study published in The Journal of Rheumatology, suggests…
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