Conditions

Subcategories:Axial Spondyloarthritis Gout and Crystalline Arthritis Guidelines Myositis Osteoarthritis and Bone Disorders Other Rheumatic Conditions Pain Syndromes Pediatric Conditions Psoriatic Arthritis Rheumatoid Arthritis Sjögren’s Disease Soft Tissue Pain Systemic Lupus Erythematosus Systemic Sclerosis Vasculitis

Study Targets Osteoclast Receptor to Inhibit Osteoclastogenesis

Lara C. Pullen, PhD | February 15, 2016

The results of a new study examined the human osteoclast-associated receptor may aid in the development of therapeutic matrikines to control aberrant osteoclastogenesis in some autoimmune diseases…

Fungal Microbiota Dysbiosis Seen in Inflammatory Bowel Disease

Anne Harding | February 13, 2016

NEW YORK (Reuters Health)—Patients with inflammatory bowel disease (IBD) show imbalance in their fungal intestinal microbiota, according to new findings. “The fungal microbiota is a new actor to take into account in the pathogenesis of IBD and potentially in other diseases,” Dr. Harry Sokol of Hospital Saint-Antoine in Paris, an author of the new study,…

Tofacitinib Decreases Inflammation in Early RA

Michele B. Kaufman, PharmD, BCGP | February 12, 2016

A recent study used MRI to show that tofacitinib reduces inflammation and inhibition of the progression of structural damage in adults with early RA…

Textile Workers at Higher Risk for Rheumatoid Arthritis

Lisa Rapaport | February 12, 2016

(Reuters Health)—Breathing textile dust on the job is linked to an almost tripled risk of developing rheumatoid arthritis (RA), a Malaysian study suggests. While smoking is a known risk factor for RA, the findings add to evidence suggesting that environmental factors could trigger RA in some people, the researchers note in their report in Annals…

Gut-on-a-Chip Provides Insight into Microbiome & Intestinal Inflammation

Lara C. Pullen, PhD | February 8, 2016

Researchers have created a microdevice with Caco-2 intestinal epithelial cells to aid in studying the human gut microbiome’s role in homeostasis, immune modulation and pathology. Using this gut-on-a-chip, researchers were able to examine in detail the processes they think result in chronic intestinal inflammation…

FDA Advisory Panel Strongly Backs Biosimilar Form of Remicade

Reuters Staff | February 6, 2016

(Reuters)—A medical advisory panel to the U.S. Food and Drug Administration on Tuesday recommended approval of a cheaper biosimilar form of Johnson & Johnson’s arthritis drug Remicade (infliximab) that could eventually batter sales of the branded product. The panel, by a vote of 21-3, supported use of the biosimilar from Celltrion Inc. and Pfizer Inc.,…

The Genetic Factor: Research Examines Genetic Heritability for Pediatric Autoimmune Diseases

Richard Quinn | February 5, 2016

Recent research has helped further define genetic heritability for pediatric autoimmune diseases. In an interview, Dr. Hakon Hakanarson discusses how understanding common genetic factors can help develop risk prediction and treatments for such diseases as juvenile idiopathic arthritis, lupus and celiac disease…

Apremilast Effective for Psoriatic Arthritis

Reuters Staff | February 2, 2016

NEW YORK (Reuters Health)—Apremilast improves clinical outcomes in patients with psoriatic arthritis and active psoriasis, according to results from the PALACE 3 randomized controlled trial. Apremilast, a phosphodiesterase 4 (PDE4) inhibitor, showed efficacy against psoriatic arthritis in the PALACE 1 trial. Dr. Christopher J. Edwards from University Hospital Southampton in the U.K. and colleagues evaluated…

Newer Biologics for RA on Par with TNF-Inhibitors for CV Risk

Laura Newman | February 2, 2016

NEW YORK (Reuters Health)—The newer disease-modifying drugs for rheumatoid arthritis appear to offer the same or even better cardiovascular (CV) protection than older tumor necrosis factor (TNF) inhibitors, hints a large study. “We really haven’t had a good understanding on where the non-TNF biologics and CV risk stand,” Dr. Jeffrey R. Curtis of the University…