Activation of peptidylarginine deiminases during complement and perforin activity may be at the core of citrullinated autoantigen production in RA.
Rheumatology Drug Updates, Trials, Safety Data
Information on acetaminophen restrictions; trials for clazakizumab, epratuzumab, romosozumab; and drug safety updates rheumatologists need to know
MicroRNA-Based Therapeutics Hold Promise Against Lupus, Other Rheumatic Diseases Note Experts at the ACR/ARHP’s 2013 Annual Meeting
Studies suggest deregulation, dysfunction of miRNAs in human, mice models of lupus may be future targets for gene therapy
Tips for Treating Pain, Depression in Patients with Rheumatic Disease Offered at the ACR/ARHP’s 2013 Annual Meeting
Observational pain scales, diagnostic tools, pharmacologic interventions, and support from psychologists, caregivers recommended
Global Perspectives on Managing Rheumatoid Arthritis Addressed at the 2013 ACR/ARHP Annual Meeting
Poverty, poor access to healthcare, cultural myths present challenges for rheumatologists caring for patients with RA in developing economic regions
Therapeutic Value of Colchicine in Osteoarthritis, Cardiovascular Disease Explored at the ACR/ARHP Winter Rheumatology Symposium
Drug’s antiinflammatory properties may help alleviate pain in patients with OA, reduce risk of myocardial infarction, but toxicity, drug interactions need to be considered
Treatment Options, Guidelines for Managing Gout Discussed at the ACR/ARHP Winter Rheumatology Symposium
Better understanding of goals, effect of gout therapy with nonsteroidal anti-inflammatory drugs, urate lowering medication needed to improve quality of care
Treating Early-Stage Spondyloarthritis May Prevent Disease Progression, Say Researchers at the ACR/ARHP Winter Rheumatology Symposium
Therapy with tumor necrosis factor inhibitors, nonsteroidal antiinflammatory drugs, ustekinumab in early stages of osteitis may halt molecular switching to bone-forming phenotype characteristic of SpA
Methotrexate May Mitigate Inflammatory Bone Disease Note Experts at the ACR/ARHP Winter Rheumatology Symposium
By regulating molecules key to osteoclast/osteoblast processes, methotrexate may reduce bone destruction in inflammatory arthritis, osteolysis, especially in combination with adenosine
Rheumatology Research Foundation to Play Role in Developing New RA, Lupus Treatments
Foundation joins Accelerating Medicines Partnership, led by National Institutes of Health, to fast-track viable potential drug therapies for lupus, rheumatoid arthritis
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