Researchers have identified 28 genome-wide significant urate concentration–associated loci, underscoring the importance of metabolic control in urate production.
Susceptibility Loci Shed Light on Fundamental Pathways of Psoriasis
Investigators have described 15 new psoriasis susceptibility loci. The loci highlight the importance of the skin in both acquired and innate host defense and identify the innate immune response as a key factor in psoriasis.
DNA Methylation Modifies Genetic Risk for Rheumatoid Arthritis
A first-of-its-kind study has been published that integrates genotype and epigenotype data across the entire genome.
Prednisone Might be the Missing Ingredient in the American College of Rheumatology’s Recommendations for Treating Patients with Rheumatoid Arthritis
A combination therapy with glucocorticoids may be the gold standard for treating patients with rheumatoid arthritis (RA)
Is Predisone 3 mg/day an Appropriate Dose for Patients with Rheumatoid Arthritis?
Long-term, low-dose prednisone at less than 5 mg/day appears tolerable and effective for many patients with rheumatoid arthritis (RA)
Why Oral Corticosteroids Should Not be Used in Patients with Rheumatoid Arthritis
Steroid use in patients with rheumatoid arthritis (RA) has been linked to higher mortality rates, greater rate of infections, more cases of pneumonia, and serious gastrointestinal events
ACR/ARHP Annual Meeting 2012: Serum Antibodies Offer Useful Clinical Insights into Systemic Sclerosis
Understanding the role of autoantibodies in systemic sclerosis (SSc) may help predict the course of the disease and guide clinical trials
ACR/ARHP Annual Meeting 2012: New Insights into Bone Erosion and Formation Heighten Prospects for Therapies
Studies look at how the balance between osteoclast-mediated bone resorption and osteoblast mediated bone formation is undermined in people with arthritic conditions
ACR/ARHP Annual Meeting 2012: Use a Combination of Tests, Patient History, and Physical Exam when Assessing Myopathies
Autoantibody testing, electromyogram, muscle tissue biopsy, and a clinical exam may help confirm a myopathy diagnosis
ACR/ARHP Annual Meeting 2012: Tips to Diagnose and Treat Catastrophic Antiphospholipid Syndrome (CAPS)
CAPS is a rare, complex disease which involves sudden clotting on multiple fronts
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