Polyarteritis nodosa (PAN) is a systemic necrotizing vasculitis that typically affects medium-sized muscular arteries. The clinical subsets of PAN are idiopathic, generalized, secondary hepatitis B virus (HBV) associated and cutaneous PAN. These clinical subsets are important because of their therapeutic implications. Virtually any organ system can be affected in generalized PAN, but this vasculitis tends…
Study Documents Breakthrough COVID-19 Infections in Vaccinated Healthcare Workers
A 2021 study demonstrated the prevalence of COVID-19 breakthrough infections in vaccinated healthcare workers, underlining the need for booster shots for this at-risk population.
In the Bones: RheumMadness 2022 False Positive MRI in Axial SpA
Spondyloarthropathy (SpA) can be difficult to diagnose, with rheumatologists sometimes relying on classification criteria designed for clinical trials. Research examines how the use of MRIs affects the finding of bone marrow edema and the diagnosis of axial SpA.
Back to Basics: RheumMadness 2022 Increasing ANA Positivity Scouting Report
Research has revealed how the prevalence of anti-nuclear antibody (ANA) positivity has changed over the past 25 years, raising questions about the role of ANA in autoimmunity and disease.
Drug Transference in Pregnancy: RheumMadness 2022 TNFi in Cord Blood Scouting Report
A study was able to quantify the transference of tumor necrosis factor (TNF) inhibitors from mother to fetus during pregnancy. Overall, the researchers found low levels of transfer for the treatments studied.
Conversation: RheumMadness 2022 Reproductive Health Guide Scouting Report
Rheumatologists play a critical role in the reproductive health of their patients, but only half of rheumatologists currently ask their patients about reproductive health or family planning issues. A new guideline seeks to change that.
Improving Bone Mineral Density: Risedronate vs. Denosumab
Treatment with denosumab for patients with RA and glucocorticoid-induced osteoporosis led to greater increases in bone mineral density of the lumbar spine and hips of patients than treatment with risedronate.
Pregnancy Outcomes in Patients with Psoriatic Arthritis
In March A&R, Remaeus et al. reported on the results of their study, which evaluated pregnancy outcomes in relation to anti-rheumatic treatment before and during pregnancy, as a proxy of disease severity in pregnant women with psoriatic arthritis (PsA), compared with those without PsA.
Get the Picture: RheumMadness 2022 PET-CT in Large Vessel Vasculitis Scouting Report
With both impressive sensitivity and specificity in capturing active large vessel vasculitis, a positron emission tomography (PET) scan is a potential tool for determining disease activity and predicting relapse in patients with large vessel vasculitis.
Another Way: RheumMadness 2022 DECT in Gout Scouting Report
Research has found dual-energy computed tomography (DECT) may be a non-invasive and cost-effective option to help rheumatologists more accurately diagnose gout.
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