Hair dye products are commonly used by both men and women to enhance youth and beauty and to follow fashion trends. As reported in the medical literature, hair dyes and their ingredients are associated with allergic contact dermatitis. A possible association with joint inflammation has also been recognized. There is literature to support that para-phenylenediamine…
FDA Approves Nintedanib for SSc-ILD, But Temper Your Expectations
The U.S. Food & Drug Administration (FDA) approved nintedanib for systemic sclerosis associated interstitial lung disease (SSc-ILD) on Sept. 6 after a randomized, controlled trial (SENSCIS) demonstrated significant benefit against placebo.1 At a cost of $96,000 per year, treatment reduced the adjusted annual rate of change in forced vital capacity (FVC) from –93.3 mL in…
Remote Use of the Multidimensional Health Assessment Questionnaire (MDHAQ)
The patient medical history is far more prominent in clinical decisions for rheumatology than for many common chronic diseases in which a gold standard biomarker, such as blood pressure or serum glucose, is applicable to diagnosis and management of all individual patients.1 Components of a subjective patient history may be recorded as structured, quantitative, standard,…
GPA & Relapsing Polychondritis Discussed
Challenges related to diagnosing chondritis are discussed.
Sicca Sleuthing: Clinical Pearls for Diagnosing & Treating Sjögren’s Syndrome
ATLANTA—Dry eyes and mouth are common symptoms in the general population. When patients report these symptoms to their primary care provider and other consultants, it may prompt a referral to a rheumatologist to rule out Sjögren’s syndrome. However, as discussed in the 2019 ACR/ARP Annual Meeting session, Sjögren’s Syndrome: Beyond the Dryness, evaluation of this…
ANCA Mortality: Are Patients Doing Better?
Patients with anti-neutrophil cytoplasmic antibody–associated vasculitides (AAV) have an increased risk of mortality. But treatments have evolved in recent years. Recent research found that between 1999 and 2017 the AAV mortality rate declined by nearly 2% per year in patients 65–74 years old…
Depression in Ankylosing Spondylitis: Mastery Is Key
A recent study indicates that depression in patients with ankylosing spondylitis is a result of both contextual and disease-related factors. Researchers found a patient’s mastery—the perception they have control over things in their lives—plays a key role in the development of depression in this patient population…
Beyond Drugs: ACR/AF Guideline Update for Hand, Knee & Hip OA Emphasizes Exercise
Guideline authors discussed therapeutic options for patients with hand, knee and hip OA in a session at the 2019 ACR/ARP Annual Meeting.
Pegloticase & Methotrexate Combination Therapy May Benefit Patients with Uncontrolled Gout
Patients with uncontrolled gout may benefit from a combination of pegloticase and methotrexate therapy, according to a small, retrospective study…
Myositis Autoantibodies: A Comparison of Serotyping Panels
The challenges of diagnosing myositis are numerous, with many tests resulting in false positives and negatives for autoantibody levels. Researchers recently compared a line blot array currently being used in research with the Oklahoma Medical Research Foundation Myositis panel, which is used in clinical testing. They found some patients were positive according to the research test, but negative according to the clinical test…
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