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Research Rheum

Recent Research: Study Summaries from Arthritis Care & Research

Meghan Angley, PhD, & S. Sam Lim, MD, Tiffany Dharia, MD, & Michael George, MD, Emily F. Neves Yuki, PhD, & Eloisa Bonfa, PhD  |  May 12, 2022

Lupus & Perinatal Outcomes Adverse perinatal outcomes before & after diagnosis with systemic lupus erythematosus among African American Women By Meghan Angley, PhD, & S. Sam Lim, MD Why was this study done? Previous studies have suggested that women with systemic lupus erythematosus (SLE) may experience adverse perinatal outcomes, including preterm and small-for-gestational-age birth, in…

Remission Definitions in RA: Common Questions & Implications for Clinical Practice

Samantha C. Shapiro, MD  |  May 5, 2022

A recent editorial provides new insights by reexamining the definitions of remission for rheumatoid arthritis and outlining concerns with the use of specific metrics for remission in clinical trials.

Outcomes in Patients with Rheumatic Diseases & COVID-19

Arthritis & Rheumatology  |  April 26, 2022

Background & objectives: Patients with rheumatic and musculoskeletal diseases (RMDs) may be at an increased risk of SARS-CO-V2 infection as a result of underlying disease, associated comorbidities and use of potentially immunosuppressive treatments. Further, concern exists regarding whether individuals with rheumatic diseases potentially experience more severe COVID-19 and poorer outcomes. This study was undertaken to…

Study: COVID-19 Vaccinations Are Safe for Patients with Lupus

Thomas R. Collins  |  April 15, 2022

COVID-19 vaccinations are safe for patients with systemic lupus erythematosus (SLE), with manageable side effects and a low incidence of flare, according to a recently published study in The Lancet.1 The use of mRNA vaccines, such as those from Pfizer-BioNTech and Moderna, which have been viewed as riskier than traditional vaccines because of a concern…

Is Hydroxychloroquine Safe During Pregnancy?

Arthritis & Rheumatology  |  March 31, 2022

Chambers et al. found no evidence of an increased risk of major structural birth defects nor any increase in a wide range of other pregnancy outcomes attributable to prenatal exposure to hydroxychloroquine.

MIPS Extreme & Uncontrollable Circumstances Application Reopened for 2021 MIPS Performance Year

the ACR RISE Registry Team  |  March 4, 2022

The CMS has reopened the MIPS Extreme and Uncontrollable Circumstances applications for groups, virtual groups and Alternative Payment Model Entities are now open through March 31.

In the Bones: RheumMadness 2022 False Positive MRI in Axial SpA

University of South Florida Rheumatology Fellowship Program: Anastasiya (Stacy) Bagrova, MD; Shreya Gor, MD; Joanne Valeriano-Marcet, MD; Larry Young, MD; & John Carter, MD  |  March 3, 2022

Spondyloarthropathy (SpA) can be difficult to diagnose, with rheumatologists sometimes relying on classification criteria designed for clinical trials. Research examines how the use of MRIs affects the finding of bone marrow edema and the diagnosis of axial SpA.

Back to Basics: RheumMadness 2022 Increasing ANA Positivity Scouting Report

University of Chicago School of Medicine: Lauren He, MD; Ana B. Arevalo, MD; & Kichul Ko, MD  |  March 3, 2022

Research has revealed how the prevalence of anti-nuclear antibody (ANA) positivity has changed over the past 25 years, raising questions about the role of ANA in autoimmunity and disease.

Drug Transference in Pregnancy: RheumMadness 2022 TNFi in Cord Blood Scouting Report

University of Chicago Medicine: Lauren He, MD; & Cuoghi Edens, MD  |  March 2, 2022

A study was able to quantify the transference of tumor necrosis factor (TNF) inhibitors from mother to fetus during pregnancy. Overall, the researchers found low levels of transfer for the treatments studied.

Conversation: RheumMadness 2022 Reproductive Health Guide Scouting Report

Duke University Rheumatology Fellowship Program: Catherine Sims, MD; Sonali Bracken, MD, PhD; Megan Milne, MD; Nathaniel Harris, MD, PhD; Poorva Apte, MD; Lena Eder, MD; Lisa Criscione-Schreiber, MD, Med; Megan Clowse, MD; & David Leverenz, MD  |  March 2, 2022

Rheumatologists play a critical role in the reproductive health of their patients, but only half of rheumatologists currently ask their patients about reproductive health or family planning issues. A new guideline seeks to change that.

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