A prospective observational study by Syversen et al. found that patients with immune-mediated inflammatory diseases (IMID) had an attenuated serologic response to the standard two-dose vaccine regimen but a third dose was safe and effective.
OA Prevalence Primarily on the Rise
Background & Objectives Worldwide, osteoarthritis (OA) is a highly prevalent, chronic joint disease that causes pain, disability and loss of function. Global trends demonstrated an increase of more than 100% in years lived with disability due to OA from 1990 to 2019. However, no nonsurgical intervention exists to prevent, halt or even delay OA progression….
We Must Include Diverse Belief Models in Rheumatology Research
Information overload generated by the media, family, friends and colleagues is apparent today. Personal beliefs play an important role in how we filter and process the abundant information available and subsequently identify its utility in daily life. Regardless of professional specialty, individual beliefs underpin personal approaches to clinical care, research development and engagement with patients…
Hand Osteoarthritis: Prevalence, Incidence and Progression
Eaton et al. set out to describe the prevalence, incidence and progression of radiographic and symptomatic hand osteoarthritis (OA), and to evaluate differences according to age, sex, race and other risk factors.
Data Accumulate to Suggest HLA-B27 Status May Drive Axial Phenotype in SpA
HLA-B27 may be a phenotypic expression of axial spondyloarthritis (SpA), according to a large international study. The study found patients with axial SpA who were positive for HLA-B27 had more severe radiographic damage than those who were negative for HLA-B27, and three quarters of study patients with ankylosis spondyloarthritis were HLA-B27 positive.
Diagnosing & Caring for Patients with Fibromyalgia
Doebl et al. compared the effect of symptoms and the healthcare use of people with fibromyalgia with those who fulfilled the criteria for fibromyalgia but had not been diagnosed and those with chronic pain. They found patients diagnosed with fibromyalgia reported the poorest healthcare experiences and were more likely than other study participants to be unemployed due to health issues. Their findings reveal an urgent need exists for a model of care for patients with fibromyalgia.
Scleroderma & the Gut: New Frontiers in Diagnosis & Tips on Management
McMahan et al. examined how abnormal gastrointestinal (GI) transit may contribute to GI severity and symptoms in patients with systemic sclerosis (SSc). About 90% of people with SSc have GI tract involvement, and understanding the connection between GI symptoms, their severity and abnormal GI transit may permit targeted therapeutic approaches for these patients.
Study: Don’t Automatically Blame Burnout on Electronic Health Records
When it comes to experiencing burnout, time spent in an electronic health records (EHR) system appears to be only a minor contributing factor. Although clinicians and other healthcare professionals may log many hours at the keyboard putting information into the EHR, other factors likely play a bigger role in the workplace exhaustion and feelings of…
Study Finds Potential Biomarkers for Cardiovascular Risk in Women with Lupus
When it comes to systemic lupus erythematosus (SLE) and cardioÂvascular events (CVEs), the rheumatology community is woefully lacking in information, say researchers from the University of California, Los Angeles (UCLA) David Geffen School of Medicine and Cedars-Sinai Medical Center. Their recent work on biomarkers associated with an increased risk for cardiovascular events in women with…
Recent Research: Study Summaries from Arthritis Care & Research
Lupus & Perinatal Outcomes Adverse perinatal outcomes before & after diagnosis with systemic lupus erythematosus among African American Women By Meghan Angley, PhD, & S. Sam Lim, MD Why was this study done? Previous studies have suggested that women with systemic lupus erythematosus (SLE) may experience adverse perinatal outcomes, including preterm and small-for-gestational-age birth, in…
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