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An official publication of the ACR and the ARP serving rheumatologists and rheumatology professionals

Research Rheum

Platelets in the Pathogenesis of SLE

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In a study, El Bannoudi et al. found that platelets contribute to the pathogenesis of SLE by secreting the proinflammatory platelet-associated lectin, galactoside-binding, soluble 3 binding protein (LGALS3BP), which also represents a novel biomarker of SLE clinical activity.

Anti-P. copri Antibody Responses in Patients with RA

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Background & Objectives Rheumatoid arthritis (RA) is a chronic autoimmune disease associated with immune responses to the patient’s own antigens and characterized by inflammation and substantial joint destruction. Prevotella copri, a gut commensal bacterium, has been reported to be an immune-relevant organism in individuals with RA. This study sought to evaluate antibody responses to anti-P….

Long COVID: Experts Weigh in on Increasingly Common Syndrome

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A minority of patients experience lingering symptoms after infec­tion with SARS-CoV-2, similar to some other previously known post-infection syndromes. Although we are just beginning to understand the differ­ent presen­tations, pathophysiology, risk factors, prognosis and treatment of long COVID, rheumatologists can play a leader­ship role in managing patients with the illness and contributing to this important research…

2022 ACR Guideline for Vaccinations in Patients with RMDs

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This guideline provides evidence-based recommendations on the use of vaccinations in children and adults with rheumatic and musculoskeletal diseases. It includes expanded indications for some vaccines, as well as guidance on whether to hold immunosuppressive medications or delay vaccination to maximize vaccine immunogenicity and efficacy.

Rheumatology Research Foundation Supports High-Risk, High-Reward Ideas

Leslie Mertz, PhD  |  

Now in the second year of his 2021–2023 term as the Rheumatology Research Foundation president, V. Michael Holers, MD, a professor of medicine and immunology and the Smyth Professor of Rheumatology at the University of Colorado, Denver, is looking forward to fortifying and expanding the Foundation’s missions in the framework of its new strategic plan.

ACR Convergence 2022 Closing Session Discusses Research Highlights

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PHILADELPHIA—Expert panelists gathered in the closing session at ACR Convergence 2022 to give their take on what they saw as some of the most notable research findings and other insights to come out of the meeting, touching on a number of topics on the leading edge of the field. COVID-19 Prophylaxis & Vaccinations Alfred Kim,…

3 AC&R Study Summaries: Treat to Target in Gout, Response to Biologics in Patients with JIA, & Rehabilitation Dose in Adults with RA

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Treat to Target in Gout Monitoring & achievement of target serum urate levels By Jing Li & Gabriela Schmajuk, MD, MS Why was this study done? The ACR’s 2020 guideline for the management of gout recommends using a treat-to-target (T2T) approach to lower serum urate (SU). Using the ACR’s RISE registry, we examined the use…

RheumMadness 2023: the All-Star Season

David L. Leverenz, MD, MEd  |  

RheumMadness is back for its third season, and everyone who is crazy about rheumatology is welcome to play. That includes practicing rheumatologists, fellows, residents, medical students, advanced practice providers, other healthcare professionals and patients. Basically, if you are reading this article, you can play RheumMadness. RheumMadness is an online tournament in which a bracket of…

How Long Should Methotrexate Be Held Following Seasonal Vaccinations?

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Vaccinations against preventable diseases, including seasonal influenza, are strongly recommended for patients with rheumatoid arthritis (RA), who are at increased risk of infections as a result of underlying immune dysfunction and treatment-induced immunosuppression. Park et al. conducted this clinical trial to investigate whether discontinuing methotrexate for one week after seasonal influenza vaccination is noninferior to discontinuing it for two weeks after vaccination in patients with RA.