Lyme disease is often considered a cause of chronic fatigue, pain and other incapacitating symptoms. This assumption stems from analyses of patients who seek retreatment for Lyme disease. However, a new study suggests that Lyme disease is not life altering in the long term for most patients. Specifically, patients with culture-confirmed Lyme disease have similar…
Anti-TNF Agents May Improve Clinical Symptoms of Ankylosing Spondylitis
Ankylosing spondylitis primarily affects the joints and ligaments of the spine, but may also have an impact on other joints. Patients experience pain and stiffness that limit mobility in the back and other affected joints. Symptoms can come and go, last for long periods of time and be severe. Anti-tumor necrosis factor (anti-TNF) drugs are…
Rising Costs of Biologics in the U.S. Suggest Need for Negotiation Ability
The costs of some disease-modifying therapies outpace prescription drug inflation, saddling insured patients with thousands of dollars in out-of-pocket payments and delayed or denied coverage, two new studies have shown. Disease-modifying therapies for multiple sclerosis are rising in cost five to seven times faster than inflation and cost more in the United States than in…
Bone Microarchitecture Impaired in Active Celiac Disease
Bone microarchitecture is impaired in premenopausal women with active celiac disease, a new study from Argentina shows. “This report helps us to understand how bone is affected in celiac disease: increasing bone resorption and thinning trabeculae, even losing some number of them,” Dr. MarĂa BelĂ©n Zanchetta from Instituto de DiagnĂłstico e Investigaciones MetabĂłlicas in Buenos…
Progress Made in Search for a Fibromyalgia Biomarker
Fibromyalgia syndrome (FMS), rheumatoid arthritis (RA) and spondyloarthritis (SpA) all exhibit multifaceted manifestations, and many patients exhibit overlapping comorbidities. However, patients with FMS are distinct from others in that they experience widespread pain, fatigue and mood changes, including anxiety and depression. Although its hallmark symptom of pain causes rheumatologists to consider FMS a pain disorder,…
Rheumatology Research Foundation Hits 30-Year Milestone
At the 2014 ACR/ARHP Annual Meeting in Boston, the Rheumatology Research Foundation staff sat down with a few ACR and ARHP members to get their take on what the Foundation’s 30th anniversary means to them. We spoke with current and former leaders of the Foundation and the ACR, as well as numerous Foundation award recipients,…
Complement Polymorphism Plays Role in RA Pathology
Study proposes increased active C5a recruits neutrophils to arthritic joints to maintain inflammation
2014 ACR/ARHP Annual Meeting: Macrophage Activation Syndrome
The pathogenesis of and new classification criteria for MAS
2014 ACR/ARHP Annual Meeting: Methotrexate Use in Patients with RA
Review of clinical research on methotrexate therapy, effect on patients’ functionality, tolerability, adverse events
2014 ACR/ARHP Annual Meeting: Super Proteins Eyed in Therapies for Rheumatic Diseases
Immunoglobulin superfamily of proteins, CTLA-4 and PD-1, may generate treatments for RA, SLE
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