Toxicity and appropriate targeting are challenges for small molecule researchers
Large Genome Study Identifies Genetic Risk Factors for Gout
Researchers have identified 28 genome-wide significant urate concentration–associated loci, underscoring the importance of metabolic control in urate production.
DNA Methylation Modifies Genetic Risk for Rheumatoid Arthritis
A first-of-its-kind study has been published that integrates genotype and epigenotype data across the entire genome.
Award Recipient Advances Rheumatology Education with e-Learning Tools
With a grant from the ACR’s Rheumatology Research Foundation, Christopher Collins, MD, is supplying e-learning tools for use in rheumatology education
ACR/ARHP Annual Meeting 2012: New Insights into Bone Erosion and Formation Heighten Prospects for Therapies
Studies look at how the balance between osteoclast-mediated bone resorption and osteoblast mediated bone formation is undermined in people with arthritic conditions
ACR/ARHP Annual Meeting 2012: Genes Not the Only Factor in Susceptibility to Rheumatoid Arthritis
Epigenetics, innate immunity, and environmental stresses such as smoking could have more influence than scientists once believed
Rheuminations: Epigenetics May Help to Explain Why Some Get Rheumatic Disease
Recent research around genes and environmental stresses suggests outside influences can make lasting changes to the genome via epigenetic mechanisms
Blue Ribbon Panel on Academic Rheumatology Publishes Final Report
Report offers recommendations to address critical issues with training, practice, and research
Research into Methotrexate Could Lead to Improved Treatments for Rheumatoid Arthritis
With a grant from the ACR’s Rheumatology Research Foundation, Nancy J. Olsen, MD, hopes to discover how methotrexate interacts with immune system cells and ultimately helps to control the system’s attack on joints
ACR/ARHP Annual Meeting 2012: Fatigue for People with Rheumatoid Arthritis Rooted in Physiological and Psychological Factors
Researchers find that genes, gender, and cognition all contribute to fatigue in rheumatoid arthritis (RA)
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