The ACR’s RISE registry offers answers on real-world experience to researchers.
What Causes Knee, Hip & Hand Osteoarthritis
Funck-Brentano et al. hypothesized that causal associations for osteoarthritis (OA) may differ by site, and they undertook this study to identify causal risk factors of knee, hip and hand OA.
Obesity, Drinking & Unhealthy Diet Add to Gout Risk
(Reuters Health)—Behavior changes could potentially reduce a large part of the risk for developing gout, a U.S. study suggests. Based on data from more than 14,000 people, researchers calculated how much factors like being overweight, following a diet that isn’t heart healthy, drinking alcohol or taking diuretics contribute to high levels of uric acid—a precursor…
Lupus Treatments: Into the Future
As the 21st century unfolds, rheumatologists will most likely transition from prescribing lupus patients broad immunosuppressants to more targeted treatment approaches. But to make this happen and advance research, the challenges experienced in lupus clinical trial design must be addressed…
Rheumatology Research Foundation Hosts Annual Investigators Meeting
The Rheumatology Research Foundation hosted the 13th annual Investigators Meeting in Washington, D.C., June 22‒23. The meeting provides Foundation-funded researchers with an opportunity to share updates on their studies, network, exchange ideas and collaborate on future projects to advance treatments and cures for rheumatic diseases. More than 50 rheumatology professionals were in attendance, with presentations…
Study Says Sjögren’s Patients Have a High Specificity for a Novel Antibody
An antibody previously un-recognized in patients with Sjögren’s syndrome may shed new light on the pathophysiology of one of the most troubling and disabling symptoms in many of these patients. Investigators at Johns Hopkins University, Baltimore, found the anti-calponin 3 antibody had a high specificity for Sjögren’s syndrome, particularly among patients with neuropathies.1 “There is…
Probing the Role of Genes & Microbiome in Ankylosing Spondylitis & RA
Researchers know human leukocyte antigen (HLA) molecules affect susceptibility to disease in general, and immunological disease in particular. In the case of ankylosing spondylitis (AS), the risk is primarily associated with HLA-B27, with smaller effects from other HLA alleles. Current thinking is that AS is caused by the presence of a genetically primed host because…
Study: Screen Hospitalized Lupus Patients for Venous Thromboembolism
When patients with lupus are hospitalized, they should be screened and likely treated for venous thromboembolism, researchers of a nationwide study say. In May, ACR Open Rheumatology published results of the large retrospective study spanning several years. Researchers analyzed trends in mortality, morbidity and hospitalization from venous thromboembolism (VTE), specifically among patients diagnosed with systemic…
Study Finds Chronic Opioid Use Doubled in Rheumatoid Arthritis Patients
The prevalence of chronic opioid use among patients with rheumatoid arthritis (RA) doubled between 2002 and 2015, especially among patients with severe pain or on antidepressants, according to a new study.1 The study adds to prior data reporting trends in chronic opioid use in RA patients.2,3 Severe pain was the strongest predictor for use of…
New Study Asks Why Lupus Patients Don’t Take Their Hydroxychloroquine
Hydroxychloroquine (HCQ) therapy may effectively manage systemic lupus erythematosus (SLE) in many patients, but that doesn’t mean patients will take it as often as they should. In fact, results from a recently published study found that about half of SLE patients were not adherent.1 The study was led by Lucy H. Liu, MD, MPH, a…
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