The rise and fall of rofecoxib and valdecoxib demonstrate the need for caution in new drug development
Treg Cells May Orchestrate Muscle Repair after Injury
New research shows the accumulation of regulatory T cells in damaged muscle corresponds with a switch in the myeloid cell infiltrate from a proinflammatory to a proregenerative phenotype.
Closer Scrutiny of Chronic Pain Patients Needed
A new study links high costs to patients with chronic pain conditions and an opioid prescription.
Improved Survival Odds Following Hip & Knee Replacements
Decreases in mortality rates following elective hip and knee replacement surgeries since 2004 may be partly due to modern surgical techniques and better pre- and post-op care.
Skin Oils Act as Natural, Tissue-Specific Autoantigens
The results of this study identify natural lipids present in the skin that augment and inhibit human T cell response, supporting the idea that lipids are T cell antigens.
Rheumatologists on the Move
Awards, appointments and announcements in the world of rheumatology
Recipients of Ephraim P. Engleman Endowed Resident Research Preceptorship Award in Rheumatology Meet Physician Who Helped Shape Their Careers
Award’s namesake, 103-year-old rheumatologist Ephraim P. Engleman, MD, met 10 winners of research funding established in his name by the Rheumatology Research Foundation in 2006
Rheuminations: Ankylosing Spondylitis Sometimes Defies Detection
How method of diagnosing, treating this inflammatory back disease characterized by stiffness and the presence of HLA-B27 gene has evolved
Rheumatologists Make Progress Defining Spectrum of Axial Spondyloarthritis
New research clarifies terminology used for diagnosis, but questions remain around epidemiology, genetics and management of patients with axial skeletal inflammation
Understanding the Role of Citrullination in Rheumatoid Arthritis
Activation of peptidylarginine deiminases during complement and perforin activity may be at the core of citrullinated autoantigen production in RA.
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