gene encoding the receptor for tumor necrosis factor (TNF) 1 is associated with multiple sclerosis (MS) but not rheumatoid arthritis (RA) or other autoimmune conditions.
In patients with simultaneous systemic and arthritic components of systemic juvenile idiopathic arthritis (SJIA), these components appear to be related mechanistically. Moreover, the inflammatory pathways of SJIA appear to be distinct from those seen in polyarticular JIA.
The Lupus Insight Prize will provide $200,000 to one researcher to help fund a project dedicated to furthering understanding of the genetic, environmental, molecular, immunologic, or cellular aspects of lupus or its treatment.