Search results for: macrophage

Fellow’s Forum Case Report: When Pulmonary Symptoms Point to Rheumatic Disease

Naina Rastalsky, MD | September 1, 2013

A 48-year-old man with diffuse arthralgias and acute respiratory failure is diagnosed with antisynthetase syndrome

President’s Perspective: The ACR and ARHP Advance Rheumatology Through International Collaboration

Audrey B. Uknis, MD, and Jan K. Richardson, PT, PhD, OCS | August 1, 2013

By forging new connections and strengthening efforts with global organizations such as EULAR, the College hopes to enhance the science, clinical care, and perceived value of rheumatology

TNF-α Impairs Regulatory T Cells in Patients with Rheumatoid Arthritis

Lara C. Pullen, PhD | June 3, 2013

When researchers treated patients with RA with TNF-α–specific antibody, they were able to restore T_reg cell function. (posted June 3, 2013)

Tofacitinib and Other Kinase Inhibitors Offer New Approach to Treating Rheumatoid Arthritis

Deborah L. Parks, MD | June 1, 2013

Small molecule kinase inhibitors, such as JAK inhibitors, provide a novel route for rheumatic disease treatment—and may promote our understanding of the immune system’s complexities

Rheuminations: Circadian Rhythms May Play Role in Inflammatory Disease

Simon M. Helfgott, MD | May 1, 2013

Research into how the timing of light and dark exposures control our lives could provide clues to why some people have immunologic disorders

ACR Winter Rheumatology Symposium: New Kinase Inhibitors Show Promise

Staff | May 1, 2013

Toxicity and appropriate targeting are challenges for small molecule researchers

Susceptibility Loci Shed Light on Fundamental Pathways of Psoriasis

Lara C. Pullen, PhD | April 26, 2013

Investigators have described 15 new psoriasis susceptibility loci. The loci highlight the importance of the skin in both acquired and innate host defense and identify the innate immune response as a key factor in psoriasis.

Speak Out Rheum: ACR/EULAR Exchange Program Expands Rheumatology Networks

Christian Beyer, MD, Neil Basu, MD, and Hans Ulrich Scherer, MD | April 1, 2013

Three young European rheumatologists share their experience in the 2012 ACR/EULAR international academic exchange program

ACR/ARHP Annual Meeting 2012: Genes Not the Only Factor in Susceptibility to Rheumatoid Arthritis

Susan Bernstein | March 1, 2013

Epigenetics, innate immunity, and environmental stresses such as smoking could have more influence than scientists once believed

Rheuminations: Epigenetics May Help to Explain Why Some Get Rheumatic Disease

Simon M. Helfgott, MD | March 1, 2013

Recent research around genes and environmental stresses suggests outside influences can make lasting changes to the genome via epigenetic mechanisms