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Search results for: diet

Effect of Diet & Sodium Intake on Serum Uric Acid

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Serum uric acid (UA) is an important factor in the causal pathway for gout. It has also been implicated as a potential risk factor and/or mediator of cardiovascular disease outcomes and mortality in a large number of observational studies. Although many of the clinical trials targeting serum UA reduction have focused on pharmacologic interventions, diet…

High-Salt Diet May Trigger Gene Silencing & a Lupus Phenotype

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New research has demonstrated that a high-salt diet may increase the differentiation of follicular helper T cells (Tfh). A high-salt diet also increased lupus features in MRL/lpr mice, suggesting that the genes that increased expression in response to salt intake were similar to the genes that had increased expression in lupus CD4+ T cells…

Role of Dietitians in Rheumatology

Deanna Yamamoto, NP, on behalf of the ARHP Practice Committee  |  

What do dietitians do to help manage patients with rheumatic disease? Dietitians are well integrated, for example, in the practice of nephrology and diabetes, but few are active in the specialty of rheumatology. However, dietitians are recognized as part of the team of providers designated to care for patients with rheumatic disease by the ACR….

Researchers Work to Untangle the Relationship Between Blood Lipids, Bone Health & Diet

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A recent editorial examined research findings on how low levels of high-density lipoprotein (HDL) in the blood affect bone health, resulting in cartilage dysfunction and the development of osteoarthritis (OA). Authors note that a high-fat diet in mice with HDL deficiency resulted in OA development; thus, they conclude that in patients with metabolic syndrome, HDL may have a causative relationship to OA…

Mediterranean Diet Tied to Lower Hip Fracture Risk

Andrew M. Seaman  |  

(Reuters Health)—Women who maintain an overall healthy diet may benefit from a slightly reduced risk of hip fractures later in life, according to a new U.S. study. Women who followed a Mediterranean-style diet were about three tenths of a percent less likely to break a hip over about 16 years, compared to women who didn’t…

Do Diet & the Environment Induce RA via ACPA Generation?

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A new study has examined how ACPA may originate at the molecular level. The researchers propose that numerous environmental factors may trigger the generation of ACPAs that then cross-react with various citrullinated human autoantigens through molecular mimicry to induce RA…

How Celebrities, Senators, Dietary Supplements Muddle Medicine

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It’s disheartening to stand by and watch helplessly as your patient dies a slow, painful death. In spring 1990, I had the misfortune of living through such a distressing experience. Strange happenings in New Mexico & Japan Ellen was a bookkeeper in her late 40s, living quietly in suburban Boston. For years, she hid a…