NEW YORK (Reuters Health)—Low-dose amitriptyline does not have clear benefits for patients with chronic low-back pain that has no specific cause, according to results from a randomized clinical trial. Despite the lack of evidence that antidepressants are more effective than placebo for low-back pain, seven of 14 national and international guidelines recommend their use in…
Search results for: pain
Pain Response to Low Intensity Pressure Tied to Cognitive Deficits in Fibromyalgia
A recent study found that the perception of experimentally induced pain is closely associated with neurocognitive symptoms, such as attention, memory and executive function, in fibromyalgia patients. Specifically, fibromyalgia patients described low-intensity pressure as more painful than controls did…
Depression Tied to Arthritis Pain
NEW YORK (Reuters Health)—Depressed individuals over age 50 should be screened for arthritis pain because the two conditions often occur together, worsening mental and physical health outcomes, researchers say. “Our findings shed light on the high rates of self-reported, doctor-diagnosed arthritis in U.S. older adults with varying degrees of depression,” Dr. Jessica Brooks of the…
Delayed Care: Research Paints Complex Picture of Treatment Delays
AMSTERDAM—A variety of factors lead to delays in patients seeking medical care for rheumatoid arthritis—from the nature of symptoms to coping tendencies—requiring more awareness from physicians when managing patients, researchers said at EULAR: the Annual European Congress of Rheumatology. Longer delays in treatment bring about more emotional distress to patients, missed chances to ease symptoms…
The FDA Denies Approval for Remoxy Extended Release; Plus Knee OA Pain Treatment Moves into Phase 3 Trials
The FDA has not approved extended release Remoxy, a gel capsule formulation of oxycodone, concluding that its potential benefits do not outweigh its risks…
Art Tours May Have Analgesic Effect for Chronic Pain Patients
(Reuters Health)—Art museums may have an analgesic effect on chronic pain, a small study suggests. Chronic pain sufferers who took guided tours of art museums felt less discomfort and unpleasantness related to their pain shortly afterward, researchers found. The researchers invited 54 visitors to the Crocker Art Museum in Sacramento, Calif., who reported experiencing chronic…
Tanezumab Promising for OA Pain; Plus, Filgotinib Investigated for Psoriatic Arthritis
New research shows tanezumab may be safe and effective for patients with osteoarthritis pain…
Anxiety, Depression May Help Predict Outcome of Low Back Pain Treatment
NEW YORK (New York)—Patients with anxiety and depression may be less satisfied than other patients with their chronic low back pain (CLBP) treatments, new research suggests. “Patients with anxiety/depression symptoms experienced more pain severity and more pain-related functional, social, and emotional disability, and they were less satisfied with care, compared with the other groups,” the…
Pfizer-Lilly Pain Drug Meets Late-Stage Trial Goals
(Reuters)—An experimental osteoarthritis drug developed by Pfizer Inc and Eli Lilly and Co achieved its main goal of lowering pain in a late stage trial, the companies said on Wednesday, potentially offering a safer alternative to opioids. Opioid abuse has reached epidemic proportions in the United States and drugmakers have been looking for less addictive…
Don’t Rule Out Placebos for Osteoarthritis Pain Control
CHICAGO—The placebo effect in treating pain in osteoarthritis (OA) should not be discounted, an expert said at the ACR State-of-the-Art Clinical Symposium in April. It’s especially important to accept the effect as real considering that trials of pain therapies in OA generate such high placebo effects (typically at least 40%) and that OA treatment options,…
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