Gout Prophylaxis: How Long Should It Continue? From the College | March 30, 2023 A strong recommendation in the 2020 American College of Rheumatology Guideline for the Management of Gout addresses the use of prophylaxis for patients starting urate-lowering therapy. Review the recommendations before you take the quiz. The 2020 American College of Rheumatology Guideline for the Management of Gout provides a strong recommendation for using concomitant anti-inflammatory prophylaxis (e.g., colchicine, non-steroidal anti-inflammatory drugs or low-dose prednisone/prednisolone) when initiating urate-lowering therapy and continuing such prophylaxis for at least: A. Three to six months B. Four to eight weeks C. Eight to 10 weeks D. One year None Time's up