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Mechanistic, Epidemiologic Clues Suggest Possible Link Between Obesity, Inflammation in Rheumatoid Arthritis

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Obesity has an established systemic inflammatory component. Could that be a trigger for the inflammation seen in rheumatoid arthritis (RA) and other rheumatic diseases? Although there is no direct scientific evidence, both mechanistic and epidemiologic clues do give some intriguing suggestions of a possible link. “At first, we thought that fat was involved only in…

Targeted Therapy for Scleroderma Fibrosis

Sara R. Schoenfeld, MD, & Flavia V. Castelino, MD  |  

Scleroderma, or systemic sclerosis (SSc), is an autoimmune disease characterized by vasculopathy and fibrosis. Although relatively rare, with a prevalence in North America of approximately 300 per 1 million people, SSc is associated with significant morbidity and high rates of mortality.1 Patients with scleroderma have four times greater mortality than age- and sex-matched controls, with…

State-of-the-Art Course on Interprofessional Management of Rheumatoid Arthritis

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During an interactive, case-based course at the 2016 ACR/ARHP Annual Meeting, participants will develop strategies to help patients manage unique barriers to access to care and adherence…

Rheumatology Drug Updates: Abaloparatide Promising for Osteoporosis, Plus Secukinumab for Ankylosing Spondylitis

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Abaloparatide for Osteoporosis Abaloparatide is completing Phase III clinical trials for the potential treatment of postmenopausal osteoporosis in women who are at an increased risk of fracture.1 Abaloparatide is a synthetic peptide that engages the parathyroid hormone receptor and has favorable bone building activity. Abaloparatide has completed Phase 3 development for use as a daily…

Rheumatologists on the Move, October 2016

Ann-Marie Lindstrom  |  

Dr. Amanda King Elected President of Caribbean Association for Rheumatology The Caribbean Association for Rheumatology (CAR) elected Amanda King, MBBS(UWI), MRCP(UK), FRCP(Glas.), president during the 7th Annual CAR Scientific Meeting this summer. This year’s CAR meeting concentrated on education for general practitioners, because there are still some islands without a rheumatologist. She is the only rheumatologist…

NYU Langone’s Division of Rheumatology in Manhattan Advances Its Mission to Understand Rheumatic Diseases, Improve Patient Outcomes

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From its beginnings as the Rheumatic Diseases Study Group (RDSG) in the early 1930s, NYU Langone Medical Center’s Division of Rheumatology has been built on a tradition of research and clinical care. Today’s division, with 24 full-time and 76 part-time faculty members, continues to push toward understanding the pathogenesis of rheumatic diseases and interventions to…

Rheumatologist, Jazz Guitarist Dr. Alan Schenk Connects with Patients, Colleagues by Playing Music

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It’s not uncommon for a new patient to arrive at the medical offices of Alan Schenk, MD, in Laguna Woods, Calif., and immediately ask him about his musical career. In addition to being a board-certified rheumatologist for the past 32 years, Dr. Schenk is also an accomplished acoustic jazz guitarist and mandolin player. Music First “I…

Preclinical Phases of Rheumatoid Arthritis Better Understood

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LONDON—Research continues to advance in understanding the causes, prediction and management of the stages of early arthritis before full-blown clinical disease, and an expert highlighted some of the latest of these encouraging findings at the Annual Congress of the European League Against Rheumatism (EULAR) 2016. Many of the genetic and environmental risk factors are known,…

Plasma Cells, Synovial Compartment Implicated in Tenacity of Rheumatoid Arthritis

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LONDON—New research shows that the synovial compartment appears to have a special role in the chronic nature of rheumatoid arthritis (RA), providing refuge for plasma cells and giving them an ideal environment in which to produce antibodies against citrullinated protein antigens (ACPA). The findings were presented at the Annual Congress of the European League Against…