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Insurance Subcommittee to the Rescue

Mary Beth Nierengarten  |  January 4, 2017

Concerned about reimbursement for specialty drugs? Wondering if your patient can continue on a prescribed medication despite formulary changes? Unsure how to request a tier exception? No need to face these issues alone. The ACR has a resource that can assist with questions regarding coverage and payment policies for private insurers and Medicare. That resource…

Filed under:Practice SupportProfessional TopicsQuality Assurance/Improvement Tagged with:ACR Insurance Subcommitteedowncodinginsurance advocacyinsurance coverageMedicarepayment policies

FDA Update: FX006 Promising for Knee OA; Pioglitazone Linked to Bladder Cancer Risk; & HIV Drug Gets New Labeling

Michele B. Kaufman, PharmD, BCGP  |  January 4, 2017

The makers of FX006, a steroid injection for treating pain in patients with knee osteoarthritis, have submitted a new drug application to the FDA…

Filed under:AnalgesicsDrug UpdatesOsteoarthritis and Bone Disorders Tagged with:CancerFDAFood and Drug AdministrationFX006HIVkneeKnee Osteoarthritis (OA)Painpioglitazone

Liquid Biopsy Provides Insights into Lupus

Lara C. Pullen, PhD  |  January 2, 2017

Microparticles in the blood of SLE patients may be a source of extracellular HMGB1, which is involved in immune response. Researchers found that analysis may be able to determine if the patient is producing dead, dying and activated cells that are important for SLE pathogenesis…

Filed under:ConditionsSystemic Lupus Erythematosus Tagged with:biopsyLupusmicroparticlessystemic lupus erythematosus (SLE)Test

New Test Yields Rapid Infliximab Drug Concentrations

Will Boggs, MD  |  December 22, 2016

NEW YORK (Reuters Health)—A new test provides rapid infliximab drug concentrations that enable immediate dosing adjustments, researchers from Belgium report. “With this rapid test, our biggest wish is to persuade physicians to now perform and use infliximab measurements also in their own daily clinical practice, as many practical and organizational issues that went along with…

Filed under:Biologics/DMARDsDrug Updates Tagged with:Biologicsdrug developmentinfliximab

Certolizumab Pegol Usage Compatible with Breastfeeding

Michele B. Kaufman, PharmD, BCGP  |  December 20, 2016

In a small-scale study, researchers found that no, or minimal amounts of, certolizumab pegol transfers from mothers taking the drug to nursing infants…

Filed under:Drug Updates Tagged with:breast milkbreastfeedingCertolizumab Pegolinfantspregnancy

The OPAL Beyond Study: Tofacitinib Phase 3 Results Positive for Treating PsA

Michele B. Kaufman, PharmD, BCGP  |  December 20, 2016

In a recent study, patients with psoriatic arthritis taking tofacitinib had a decrease in disease activity compared with placebo…

Filed under:ConditionsDrug UpdatesPsoriatic Arthritis Tagged with:Disease-modifying antirheumatic drugs (DMARDs)Janus Kinase InhibitorsPsoriatic ArthritisTofacitinib

The Future of Pediatric Rheumatology Grounded in Evolution of Childhood Arthritis and Rheumatology Research Alliance

Yukiko Kimura, MD, & Laura E. Schanberg, MD  |  December 15, 2016

Pediatric rheumatology was formally recognized as a specialty in 1991 by the American Board of Pediatrics. Prior to this time, children with rheumatic diseases were treated by a hodgepodge of providers. In addition to providers who had training as pediatric rheumatologists, general pediatricians, adult rheumatologists, allergist-immunologists, orthopedists, pediatric infectious disease specialists and others treated children…

Filed under:ConditionsPediatric ConditionsProfessional TopicsProfiles Tagged with:CARRAChildhood Arthritis & Rheumatology Research AlliancefutureHistorypatient carePediatricProfilerheumatology

Rheumatology Case Report: Systemic Capillary Leak Syndrome and Rheumatoid Arthritis

Alexis Smith, MD, & Angus Worthing, MD, FACP, FACR  |  December 15, 2016

Systemic capillary leak syndrome (SCLS) is a very rare disorder, characterized by recurrent episodes of severe hypotension, hypoalbuminemia and hemoconcentration.1 Attacks of SCLS occur in three phases: 1) prodrome; 2) hypovolemia with weight gain; and 3) hypervolemia with fluid overload and polyuria often complicated by pulmonary edema. Often, compartment syndrome can lead to rhabdomyolysis as…

Filed under:ConditionsRheumatoid Arthritis Tagged with:case reportconditionsoutcomepatient careRheumatoid arthritisrheumatologysystemic capillary leak syndromeTreatment

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Assessing Autoimmune Disease Symptoms in Silicone Breast Implant Recipients

Charles Radis, DO  |  December 15, 2016

My nurse, Joanne, took me aside before I began my next consult. “Room No. 5, breast implant patient. Her lawyer organized the records.” She handed me a hefty three-ring notebook organized by color-coded tabs. “Her attorney called just now,” Joanne raised an eyebrow, “and told me to tell you that, to save time, he highlighted…

Filed under:ConditionsSystemic Lupus Erythematosus Tagged with:Autoimmune diseasebreast implantDiagnosisLupuspatient carephysicianrheumatologistsiliconeSLEsymptom

Infection Greater Worry Than Flare: Collaborative Guideline Offers Guidance to Prevent Joint Replacement Complications & Failure

Susan Bernstein  |  December 14, 2016

WASHINGTON, D.C.—Total joint arthroplasty is one of the most common surgical procedures performed on adults with end-stage arthritis. One recent estimate showed that 2.5 million individuals in the U.S. are living with a total hip replacement and 4.7 million are living with knee replacements. For their patients with inflammatory arthritis, rheumatologists and orthopedic surgeons must…

Filed under:Clinical Criteria/GuidelinesMeeting ReportsProfessional Topics Tagged with:2016 ACR/ARHP Annual Meetingdraft guidelineguideline projectjoint implant failurePerioperative Management of Anti-Rheumatic Medications in Patients with Rheumatic Diseases Undergoing Elective Total Hip or Knee Arthroplastyperioperative periodpostoperative infection

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